Universality of phenotypic distributions in bacteria
Some phenotypic properties in bacteria exhibit universal statistics, with distributions
collapsing under scaling. The extent and origins of such universality are not well …
collapsing under scaling. The extent and origins of such universality are not well …
Characterizing non-exponential growth and bimodal cell size distributions in fission yeast: An analytical approach
Unlike many single-celled organisms, the growth of fission yeast cells within a cell cycle is
not exponential. It is rather characterized by three distinct phases (elongation, septation, and …
not exponential. It is rather characterized by three distinct phases (elongation, septation, and …
Continuous rate modeling of bacterial stochastic size dynamics
Bacterial division is an inherently stochastic process with effects on fluctuations of protein
concentration and phenotype variability. Current modeling tools for the stochastic short-term …
concentration and phenotype variability. Current modeling tools for the stochastic short-term …
Stochastic threshold in cell size control
L Luo, Y Bai, X Fu - Physical Review Research, 2023 - APS
Classic models of cell size control consider that cells divide when reaching a threshold, eg,
size, age, or size extension. The molecular basis of the threshold involves multiple layers of …
size, age, or size extension. The molecular basis of the threshold involves multiple layers of …
Pyecolib: a python library for simulating stochastic cell size dynamics
Recently, there has been an increasing need for tools to simulate cell size regulation due to
important applications in cell proliferation and gene expression. However, implementing the …
important applications in cell proliferation and gene expression. However, implementing the …
Joint distribution of protein concentration and cell volume coupled by feedback in dilution
We consider a protein that negatively regulates the rate with which a cell grows. Since less
growth means less protein dilution, this mechanism forms a positive feedback loop on the …
growth means less protein dilution, this mechanism forms a positive feedback loop on the …
Concentration fluctuations due to size-dependent gene expression and cell-size control mechanisms
Intracellular reaction rates depend on concentrations and hence their levels are often
regulated. However classical models of stochastic gene expression lack a cell size …
regulated. However classical models of stochastic gene expression lack a cell size …
Cell size control shapes fluctuations in colony population
Exponentially growing cells regulate their size by controlling their timing of division. Since
two daughter cells are born as a result of this cell splitting, cell size regulation has a direct …
two daughter cells are born as a result of this cell splitting, cell size regulation has a direct …
Large deviations and fluctuation theorems for cycle currents defined in the loop-erased and spanning tree manners: a comparative study
The cycle current is a crucial quantity in stochastic thermodynamics. The absolute and net
cycle currents of a Markovian system can be defined in the loop-erased (LE) or spanning …
cycle currents of a Markovian system can be defined in the loop-erased (LE) or spanning …
Branching processes with resetting as a model for cell division
A Genthon, R García-García… - Journal of Physics A …, 2022 - iopscience.iop.org
We study the stochastic thermodynamics of cell growth and division using a theoretical
framework based on branching processes with resetting. Cell division may be split into two …
framework based on branching processes with resetting. Cell division may be split into two …