Evolution of the mammalian G protein α subunit multigene family
TM Wilkie, DJ Gilbert, AS Olsen, XN Chen… - Nature …, 1992 - nature.com
Heterotrimeric guanine nucleotide binding proteins (G proteins) transduce extracellular
signals received by transmembrane receptors to effector proteins. The multigene family of G …
signals received by transmembrane receptors to effector proteins. The multigene family of G …
Role of subunit diversity in signaling by heterotrimeric G proteins
JD Hildebrandt - Biochemical pharmacology, 1997 - Elsevier
The heterotrimeric G proteins are extensively involved in the regulation of cells by
extracellular signals. The receptors that control them are often the targets of drugs. There are …
extracellular signals. The receptors that control them are often the targets of drugs. There are …
Familial cylindromatosis (turban tumour syndrome) gene localised to chromosome 16q12–q13: evidence for its role as a tumour suppressor gene
PJ Biggs, R Wooster, D Ford, P Chapman, J Mangion… - Nature …, 1995 - nature.com
The human skin is a complex organ composed of the surface epidermis, the subjacent
dermis (in which blood vessels, lymphatics and nerves are located) and the skin …
dermis (in which blood vessels, lymphatics and nerves are located) and the skin …
Molecular mechanisms of go signaling
M Jiang, NS Bajpayee - Neurosignals, 2009 - karger.com
Go is the most abundant G protein in the central nervous system, where it comprises about
1% of membrane protein in mammalian brains. It functions to couple cell surface receptors to …
1% of membrane protein in mammalian brains. It functions to couple cell surface receptors to …
The oncogenic polycomb histone methyltransferase EZH2Methylates Lysine 120 on Histone H2B and competes ubiquitination
M Kogure, M Takawa, V Saloura, K Sone, L Piao… - Neoplasia, 2013 - Elsevier
The histone methyltransferase enhancer of zeste 2 (EZH2) is known to be a polycomb
protein homologous to Drosophila enhancer of zeste and catalyzes the addition of methyl …
protein homologous to Drosophila enhancer of zeste and catalyzes the addition of methyl …
[HTML][HTML] Guanine nucleotide-binding proteins in the intestinal parasite Giardia lamblia. Isolation of a gene encoding an approximately 20-kDa ADP-ribosylation factor.
JJ Murtagh Jr, MR Mowatt, CM Lee, FJ Lee… - Journal of Biological …, 1992 - Elsevier
Giardia lamblia is a protozoan intestinal parasite that has characteristics of both eukaryotes
and prokaryotes. To determine whether genes for guanine nucleotide-binding proteins are …
and prokaryotes. To determine whether genes for guanine nucleotide-binding proteins are …
Regulation of gene expression for translation initiation factor eIF-2α: importance of the 3′ untranslated region
S MIYAMOTO, JA CHIORINI, E URCELAY… - Biochemical …, 1996 - portlandpress.com
Gene expression of the α-subunit of eukaryotic initiation factor-2 (eIF-2α), involves
transcriptional and post-transcriptional mechanisms. eIF-2α is a single-copy gene …
transcriptional and post-transcriptional mechanisms. eIF-2α is a single-copy gene …
Posttranslational modification of Gαo1 generates Gαo3, an abundant G protein in brain
Gαo, the most abundant G protein in mammalian brain, occurs at least in two subforms, ie,
Gαo1 and Gαo2, derived by alternative splicing of the mRNA. A third Gαo1-related isoform …
Gαo1 and Gαo2, derived by alternative splicing of the mRNA. A third Gαo1-related isoform …
Cell-specific dendritic localization of glycine receptor α subunit messenger RNAs
The regional and subcellular localizations of glycine receptor complex messenger RNAS
were determined in the adult rat central nervous system using non-radioactive in situ …
were determined in the adult rat central nervous system using non-radioactive in situ …
High-resolution cytogenetic-based physical map of human chromosome 16
A panel of 54 mouse/human somatic cell hybrids, each possessing various portions of
chromosome 16, was constructed; 46 were constructed from naturally occurring …
chromosome 16, was constructed; 46 were constructed from naturally occurring …