Cannabis extracts have been used for centuries, but its main active principle∆ 9-
tetrahydrocannabinol (THC) was identified about 50 years ago. Yet, it is only 25 years ago …

The endocannabinoid system is up-regulated in numerous pathophysiological states such
as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular …

Inspired by the medicinal properties of the plant Cannabis sativa and its principal
component (−)-trans-Δ9-tetrahydrocannabinol (THC), researchers have developed a variety …

Monoglyerides (MGs) are short-lived, intermediary lipids deriving from the degradation of
phospho-and neutral lipids, and monoglyceride lipase (MGL), also designated as …

The endocannabinoid system (ECS) comprises two cognate endocannabinoid receptors
referred to as CB1R and CB2R. ECS dysregulation is apparent in neurodegenerative/neuro …

The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …

Although the endocannabinoid system (ECS) is involved in the regulation of several
physiological processes, including sleep and the immune response, its role during infections …

Since the discovery of the endocannabinoid system consisting of cannabinoid receptors,
endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been …

Cannabis, as a natural medicinal remedy, has long been used for palliative treatment to
alleviate the side effects caused by diseases. Cannabis-based products isolated from plant …

Opportunities for developing innovative and intelligent drug delivery technologies by
targeting the endocannabinoid system are becoming more apparent. This review provides …