Diosgenin: an updated pharmacological review and therapeutic perspectives

P Semwal, S Painuli, T Abu-Izneid… - Oxidative Medicine …, 2022 - Wiley Online Library
Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Wogonin and its analogs for the prevention and treatment of cancer: A systematic review

K Banik, E Khatoon, C Harsha, V Rana… - Phytotherapy …, 2022 - Wiley Online Library
The medicinal plant Scutellaria baicalensis, commonly known as Chinese skullcap or
Huang‐Qin, has been used as a traditional medicine for several thousand years. The roots …

COVID-19, cytokines, inflammation, and spices: How are they related?

AB Kunnumakkara, V Rana, D Parama, K Banik… - Life sciences, 2021 - Elsevier
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

[HTML][HTML] Saponins: A concise review on food related aspects, applications and health implications

K Sharma, R Kaur, S Kumar, RK Saini, S Sharma… - Food Chemistry …, 2023 - Elsevier
In recent years, saponins are gaining extensive attention due to their occurrence in several
plants. Saponins and their derivatives are versatile glycosidic compounds, which play an …

[HTML][HTML] Biological and pharmacological effects of synthetic saponins

YP Juang, PH Liang - Molecules, 2020 - mdpi.com
Saponins are amphiphilic molecules consisting of carbohydrate and either triterpenoid or
steroid aglycone moieties and are noted for their multiple biological activities—Fungicidal …

Rationalizing the therapeutic potential of apigenin against cancer

SA Ahmed, D Parama, E Daimari, S Girisa, K Banik… - Life Sciences, 2021 - Elsevier
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …

Xanthohumol from Hop: Hope for cancer prevention and treatment

S Girisa, Q Saikia, D Bordoloi, K Banik, J Monisha… - IUBMB …, 2021 - Wiley Online Library
Cancer is a major public health concern due to high mortality and poor quality of life of
patients. Despite the availability of advanced therapeutic interventions, most treatment …

Natural compounds targeting nuclear receptors for effective cancer therapy

M Hegde, S Girisa, N Naliyadhara, A Kumar… - Cancer and Metastasis …, 2023 - Springer
Human nuclear receptors (NRs) are a family of forty-eight transcription factors that modulate
gene expression both spatially and temporally. Numerous biochemical, physiological, and …

Current clinical developments in curcumin‐based therapeutics for cancer and chronic diseases

A Kumar, C Harsha, D Parama, S Girisa… - Phytotherapy …, 2021 - Wiley Online Library
The last decade has seen an unprecedented rise in the prevalence of chronic diseases
worldwide. Different mono‐targeted approaches have been devised to treat these multigenic …