Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …

Alcoholic liver disease (ALD) refers to the damages to the liver and its functions due to
alcohol overconsumption. It consists of fatty liver/steatosis, alcoholic hepatitis …

Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …

Background & Aims The degree of cholestasis is an important disease driver in alcoholic
hepatitis, a severe clinical condition that needs new biomarkers and targeted therapies. We …

Importance Traditionally, liver transplant (LT) for alcohol-associated liver disease (ALD)
requires 6 months of abstinence. Although early LT before 6 months of abstinence has been …

Bile acids (BAs) activate various dedicated receptors, including the farnesoid X receptor
(FXR) and the Takeda G protein‐coupled receptor 5 (TGR5). The FXR agonist obeticholic …

Targeted therapy is an emerging treatment strategy for alcoholic liver disease (ALD).
Inflammation plays an important role in the occurrence and development of ALD, and is a …

Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic
or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is …

Alcoholic liver disease is highly prevalent but poorly identified and characterized, leading to
knowledge gaps, which impairs early diagnosis. Excessive alcohol consumption is known to …

Alcohol-associated liver disease (ALD) is a global health issue and leads to progressive
liver injury, comorbidities, and increased mortality. Human-relevant preclinical models of …