[HTML][HTML] Pharmacotherapy for Dravet syndrome: a systematic review and network meta-analysis of randomized controlled trials

S Lattanzi, E Trinka, E Russo, C Del Giovane… - Drugs, 2023 - Springer
Background Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy
characterized by drug-resistant, lifelong seizures. The management of seizures in DS has …

[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease

WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …

Cenobamate in refractory epilepsy: Overview of treatment options and practical considerations

B Schmitz, S Lattanzi, K Vonck, R Kälviäinen… - Epilepsia …, 2023 - Wiley Online Library
Management of drug resistant epilepsy (DRE) represents a challenge to the treating
clinician. This manuscript addresses DRE and provides an overview of treatment options …

Futile recanalization is associated with increased risk of post-stroke epilepsy

S Lattanzi, C Cuccurullo, N Orlandi, G Borzì… - Journal of the …, 2024 - Elsevier
Background Endovascular treatment (EVT) is the standard of care of ischaemic stroke due to
occlusion of large vessels. Although EVT can significantly improve short-and long-term …

NIR‐II Fluorescence Sensor Based on Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy Visualization

M Zhao, W Lai, B Li, T Bai, C Liu, Y Lin… - Angewandte Chemie …, 2024 - Wiley Online Library
Fluorescence sensing is crucial to studying biological processes and diagnosing diseases,
especially in the second near‐infrared (NIR‐II) window with reduced background signals …

Proceedings of the “International Congress on Structural Epilepsy & Symptomatic Seizures”(STESS, Gothenburg, Sweden, 29–31 March 2023)

F Brigo, J Zelano, L Abraira, C Bentes, CT Ekdahl… - Epilepsy & Behavior, 2024 - Elsevier
In 2019, over 130 people from several countries travelled to Gothenburg, Sweden, for the
Seizures and Stroke Congress, the first international conference devoted to post-stroke …

Acute symptomatic seizures after stroke: A scoping review on primary prevention, treatment with antiseizure medications and drug discontinuation

G Zaccara, S Lattanzi, F Brigo - Epilepsy & Behavior, 2023 - Elsevier
Aim To evaluate and synthesize the evidence and knowledge gaps on primary prevention
and treatment of post-stroke acute symptomatic seizures (ASSs) using antiseizure …

[HTML][HTML] Natural products in the treatment of neurological diseases: identification of novel active compounds and therapeutic targets

J Zhao, D Wang, W Cui, H Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Stroke, epilepsy, and depression rank among the most prevalent neurological and
psychiatric disorders, yet viable treatment options remain limited (Campbell and Khatri …

Reproductive and fetal toxicity studies of histamine H3 receptor antagonist DL76 used in mice to prevent maximal electroshock-induced seizure

SM Bastaki, YM Abdulrazzaq, MA Zidan… - Frontiers in …, 2024 - frontiersin.org
Introduction: Brain histamine is considered an endogenous anticonvulsant and histamine
H1 receptor. H1R antagonists have, in earlier studies, been found to induce convulsions …

[HTML][HTML] Neuromodulation for pharmacoresistant epilepsy: from bench to bed

T Li, J Deng, J Qin, XP Chu - Frontiers in Neurology, 2024 - frontiersin.org
Epilepsy is a persistent neurological disorder that affects more than 70 million people
worldwide. It is characterized by a long-lasting predisposition to recurrently generate …