Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Background Major psychiatric disorders are growing public health concern that attributed
14% of the global burden of diseases. The management of major psychiatric disorders is …

A number of effective maintenance medication options exist for bipolar disorder (BD) and
these are regarded as the foundation of long-term treatment in BD. However, nonadherence …

Although some studies have suggested that relapse may be associated with antipsychotic
treatment resistance in schizophrenia, the number and quality of studies is limited. The …

Background: This double-blind, parallel-group, multicenter, phase-3 study was designed to
test the noninferiority of paliperidone palmitate 3-month formulation (PP3M) to the currently …

Background Medication non-adherence is one of the major challenges in treating patients
with depression. This systematic review aims to determine the clinical and economic …

Objective: Antipsychotic medication non-adherence has detrimental effects on patients'
clinical outcome. It is unclear which risk factors affect adherence most and which …

Schizophrenia is a serious mental illness that requires continuous and effective long-term
management to reduce symptoms, improve quality of life, and prevent relapse. Oral …

Implantable drug-eluting devices that provide therapeutic cover over an extended period of
time following a single administration have potential to improve the treatment of chronic …

Background: Medication adherence is critical to the effectiveness of psychopharmacologic
therapy. Psychiatric disorders present special adherence considerations, notably an altered …