Advances in cutaneous squamous cell carcinoma

MCG Winge, LN Kellman, K Guo, JY Tang… - Nature Reviews …, 2023 - nature.com
Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

Update on keratinocyte carcinomas

KS Nehal, CK Bichakjian - New England Journal of Medicine, 2018 - Mass Medical Soc
Update on Keratinocyte Carcinomas | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

[HTML][HTML] Multimodal analysis of composition and spatial architecture in human squamous cell carcinoma

AL Ji, AJ Rubin, K Thrane, S Jiang, DL Reynolds… - Cell, 2020 - cell.com
To define the cellular composition and architecture of cutaneous squamous cell carcinoma
(cSCC), we combined single-cell RNA sequencing with spatial transcriptomics and …

Pembrolizumab monotherapy for recurrent or metastatic cutaneous squamous cell carcinoma: a single-arm phase II trial (KEYNOTE-629)

JJ Grob, R Gonzalez, N Basset-Seguin… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Treatment options are limited for patients with recurrent and/or metastatic (R/M)
cutaneous squamous cell carcinoma (cSCC); mortality rates exceed 70% in patients with …

[HTML][HTML] European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 2. Treatment

AJ Stratigos, C Garbe, C Dessinioti, C Lebbe… - European Journal of …, 2020 - Elsevier
In order to update recommendations on treatment, supportive care, education and follow-up
of patients with invasive cutaneous squamous cell carcinoma (cSCC), a multidisciplinary …

Guidelines of care for the management of cutaneous squamous cell carcinoma

M Alam, A Armstrong, C Baum, JS Bordeaux… - Journal of the American …, 2018 - Elsevier
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human
cancer and has an increasing annual incidence. Although most cSCC is cured with office …

Cemiplimab in locally advanced cutaneous squamous cell carcinoma: results from an open-label, phase 2, single-arm trial

MR Migden, NI Khushalani, ALS Chang… - The lancet …, 2020 - thelancet.com
Background Cemiplimab has shown substantial antitumour activity in patients with
metastatic cutaneous squamous cell carcinoma. Patients with locally advanced cutaneous …

[HTML][HTML] Diagnosis and treatment of invasive squamous cell carcinoma of the skin: European consensus-based interdisciplinary guideline

A Stratigos, C Garbe, C Lebbe, J Malvehy… - European journal of …, 2015 - Elsevier
Cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in
Caucasian populations, accounting for 20% of all cutaneous malignancies. A unique …

Phase II study of pembrolizumab as first-line, single-drug therapy for patients with unresectable cutaneous squamous cell carcinomas

E Maubec, M Boubaya, P Petrow… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To evaluate first-line pembrolizumab monotherapy efficacy and safety in patients
with unresectable cutaneous squamous cell carcinomas (CSCCs). PATIENTS AND …

Cutaneous squamous cell carcinoma: a review of high-risk and metastatic disease

KA Burton, KA Ashack, A Khachemoune - American journal of clinical …, 2016 - Springer
Non-melanoma skin cancer represents one-third of all malignancies and its incidence is
expected to rise until the year 2040. Cutaneous squamous cell carcinoma (cSCC) …