Liver fibrosis resolution: from molecular mechanisms to therapeutic opportunities

Q Pei, Q Yi, L Tang - International Journal of Molecular Sciences, 2023 - mdpi.com
The liver is a critical system for metabolism in human beings, which plays an essential role
in an abundance of physiological processes and is vulnerable to endogenous or exogenous …

[HTML][HTML] Role of circular RNAs and gut microbiome in gastrointestinal cancers and therapeutic targets

ST Abdullah, SR Abdullah, BM Hussen… - Non-coding RNA …, 2023 - Elsevier
Gastrointestinal cancers are a huge worldwide health concern, which includes a wide
variety of digestive tract cancers. Circular RNAs (circRNAs), a kind of non-coding RNA …

Circular RNAs in Cell Cycle Regulation of Cancers

P Thamjamrassri, C Ariyachet - International Journal of Molecular …, 2024 - mdpi.com
Cancer has been one of the most problematic health issues globally. Typically, all cancers
share a common characteristic or cancer hallmark, such as sustaining cell proliferation …

CircUTRN24/miR-483-3p/IGF-1 regulates autophagy mediated liver fibrosis in biliary atresia

D Liu, Z Wu, J Gao, Q Mei, X Zhang, B Wang - Molecular Biotechnology, 2024 - Springer
Biliary atresia (BA) is a rare neonatal cholestatic disease that presents with a marked bile
duct reaction and rapid fibrotic development. Our earlier research has shown that …

The mechanisms and therapeutic potential of long noncoding RNA NEAT1 in fibrosis

X Jiang - Clinical and Experimental Medicine, 2023 - Springer
Fibrosis is the excess deposition of extracellular matrix involved in the pathogenesis of
chronic diseases and finally leads to the disruption of tissue architecture and failure of organ …

[HTML][HTML] Mechanisms of Epigenetic Regulation in the Fibrogenic Activation of Hepatic Stellate Cells in Non-alcoholic Fatty Liver Disease

DV Garbuzenko - Gene Expression, 2024 - xiahepublishing.com
Non-alcoholic fatty liver disease (NAFLD) is an extremely prevalent disease, and the
presence and severity of liver fibrosis are considered one of the most important factors …