2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: a report of the American College of Cardiology/American …

SR Ommen, S Mital, MA Burke, SM Day… - The Journal of thoracic …, 2021 - jtcvs.org
Guidelines Liaison; cHFSA Representative; dASE Representative; eHRS Representative;
fSCMR Representative; gAATS Representative; hSCAI Representative; and iFormer Joint …

Pathophysiology and treatment of hypertrophic cardiomyopathy: new perspectives

M Zampieri, M Berteotti, C Ferrantini, L Tassetti… - Current heart failure …, 2021 - Springer
Abstract Purpose of Review We provide a state of the art of therapeutic options in
hypertrophic cardiomyopathy (HCM), focusing on recent advances in our understanding of …

Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes

DY Barefield, P Tonino, KC Woulfe… - Proceedings of the …, 2023 - National Acad Sciences
Mutations in atrial-enriched genes can cause a primary atrial myopathy that can contribute to
overall cardiovascular dysfunction. MYBPHL encodes myosin-binding protein H-like (MyBP …

Contemporary therapies and future directions in the management of hypertrophic cardiomyopathy

E Packard, A de Feria, S Peshin, N Reza… - Cardiology and …, 2022 - Springer
Hypertrophic cardiomyopathy (HCM) is a genetic disorder caused by pathogenic variants in
sarcomeric genes, leading to left ventricular hypertrophy and complex phenotypic …

Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy

R Coppini, L Santini, I Olivotto… - Cardiovascular …, 2020 - academic.oup.com
Hypertrophic cardiomyopathy (HCM) is a common inherited monogenic disease with a
prevalence of 1/500 in the general population, representing an important cause of …

Familial hypertrophic cardiomyopathy: diagnosis and management

MJ Litt, A Ali, N Reza - Vascular health and risk management, 2023 - Taylor & Francis
Hypertrophic cardiomyopathy (HCM) is widely recognized as one of the most common
inheritable cardiac disorders. Since its initial description over 60 years ago, advances in …

Prognostic value of myocardial extracellular volume fraction evaluation based on cardiac magnetic resonance T1 mapping with T1 long and short in hypertrophic …

Y Li, X Liu, F Yang, J Wang, Y Xu, TT Fang, LT Pu… - European …, 2021 - Springer
Objective To investigate the prognostic significance of T1 mapping using T1 long and short
in hypertrophic cardiomyopathy (HCM) patients. Methods A total of 263 consecutive patients …

Multi-omic architecture of obstructive hypertrophic cardiomyopathy

R Garmany, JM Bos, DJ Tester… - Circulation: Genomic …, 2023 - Am Heart Assoc
Background: Hypertrophic cardiomyopathy (HCM) is characterized by asymmetric left
ventricular hypertrophy. Currently, hypertrophy pathways responsible for HCM have not …

Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine

MJ Greenberg, JC Tardiff - Journal of General Physiology, 2021 - rupress.org
Genetic cardiomyopathies have been studied for decades, and it has become increasingly
clear that these progressive diseases are more complex than originally thought. These …

Novel therapies for prevention and early treatment of cardiomyopathies: now and in the future

GG Repetti, CN Toepfer, JG Seidman… - Circulation …, 2019 - Am Heart Assoc
Heritable cardiomyopathies are a class of heart diseases caused by variations in a number
of genetic loci. Genetic variants on one allele lead to either a degraded protein, which …