A thousand-genome panel retraces the global spread and adaptation of a major fungal crop pathogen

A Feurtey, C Lorrain, MC McDonald, A Milgate… - Nature …, 2023 - nature.com
Human activity impacts the evolutionary trajectories of many species worldwide. Global
trade of agricultural goods contributes to the dispersal of pathogens reshaping their genetic …

CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae

J Huang, D Rowe, P Subedi, W Zhang… - Nature …, 2022 - nature.com
CRISPR-Cas mediated genome engineering has revolutionized functional genomics.
However, understanding of DNA repair following Cas-mediated DNA cleavage remains …

Giant Starship Elements Mobilize Accessory Genes in Fungal Genomes

E Gluck-Thaler, T Ralston, Z Konkel… - Molecular biology …, 2022 - academic.oup.com
Accessory genes are variably present among members of a species and are a reservoir of
adaptive functions. In bacteria, differences in gene distributions among individuals largely …

Recent transposable element bursts are associated with the proximity to genes in a fungal plant pathogen

U Oggenfuss, D Croll - PLoS Pathogens, 2023 - journals.plos.org
The activity of transposable elements (TEs) contributes significantly to pathogen genome
evolution. TEs often destabilize genome integrity but may also confer adaptive variation in …

Recent reactivation of a pathogenicity-associated transposable element is associated with major chromosomal rearrangements in a fungal wheat pathogen

T Badet, SM Tralamazza, A Feurtey… - Nucleic Acids …, 2024 - academic.oup.com
Transposable elements (TEs) are key drivers of genomic variation contributing to recent
adaptation in most species. Yet, the evolutionary origins and insertion dynamics within …

Transposable elements impact the population divergence of rice blast fungus Magnaporthe oryzae

L Lin, T Sun, J Guo, L Lin, M Chen, Z Wang, J Bao… - Mbio, 2024 - Am Soc Microbiol
Dynamic transposition of transposable elements (TEs) in fungal pathogens has significant
impact on genome stability, gene expression, and virulence to the host. In Magnaporthe …

The landscape and predicted roles of structural variants in Fusarium graminearum genomes

U Dhakal, HS Kim, C Toomajian - G3 Genes| Genomes …, 2024 - academic.oup.com
Structural rearrangements, such as inversions, translocations, duplications, and large
insertions and deletions, are large-scale genomic variants that can play an important role in …

The Egyptian wheat cultivar Gemmeiza-12 is a source of resistance against the fungus Zymoseptoria tritici

AM Qutb, F Cambon, MC McDonald, C Saintenac… - BMC Plant …, 2024 - Springer
Background Wheat is one of the world's most important cereal crops. However, the fungal
pathogen Zymoseptoria tritici can cause disease epidemics, leading to reduced yields. With …

Comparative transcriptome reveals importance of export apparatus subunit (ascR) in type III secretion system and its roles on biological properties, gene expression …

X Tang, Q Yang, S Hu, K Guo, Y Li, Z Wu - International Journal of …, 2024 - Elsevier
Aeromonas veronii, an opportunistic pathogen, is known to cause serious infections across
various species. In our previous study, we discovered that A. veronii GL2 exhibited a …

Recurrent chromosome destabilization through repeat-mediated rearrangements in a fungal pathogen

S Fouche, U Oggenfuss, BA McDonald, D Croll - bioRxiv, 2023 - biorxiv.org
Genomic instability caused by chromosomal rearrangements has severe consequences for
organismal fitness and progression of cancerous cell lines. The triggers of destabilized …