[HTML][HTML] Diffusion tensor imaging and plasma immunological biomarker panel in a rat traumatic brain injury (TBI) model and in human clinical TBI

XV To, AZ Mohamed, P Cumming… - Frontiers in …, 2024 - frontiersin.org
Introduction Neuroinflammatory reactions play a significant role in the pathology and long-
term consequences of traumatic brain injury (TBI) and may mediate salutogenic processes …

CACTUS: a computational framework for generating realistic white matter microstructure substrates

JL Villarreal-Haro, R Gardier… - Frontiers in …, 2023 - frontiersin.org
Monte-Carlo diffusion simulations are a powerful tool for validating tissue microstructure
models by generating synthetic diffusion-weighted magnetic resonance images (DW-MRI) in …

[HTML][HTML] Escalation of tau accumulation after a traumatic brain injury: findings from positron emission tomography

AZ Mohamed, P Cumming, FA Nasrallah… - Brain Sciences, 2022 - mdpi.com
Traumatic brain injury (TBI) has come to be recognized as a risk factor for Alzheimer's
disease (AD), with poorly understood underlying mechanisms. We hypothesized that a …

[HTML][HTML] Neutrophil-derived interleukin-17A participates in neuroinflammation induced by traumatic brain injury

XJ Xu, QQ Ge, MS Yang, Y Zhuang… - Neural Regeneration …, 2023 - journals.lww.com
After brain injury, infiltration and abnormal activation of neutrophils damages brain tissue
and worsens inflammation, but the mediators that connect activated neutrophils with …

[HTML][HTML] Association of sub-acute changes in plasma amino acid levels with long-term brain pathologies in a rat model of moderate-severe traumatic brain injury

XV To, AZ Mohamed, P Cumming… - Frontiers in …, 2023 - frontiersin.org
Introduction Traumatic brain injury (TBI) induces a cascade of cellular alterations that are
responsible for evolving secondary brain injuries. Changes in brain structure and function …

Evaluating Microglia Dynamics in Blast and Impact-Induced Neurotrauma and Assessing the Role of Hemostatic Nanoparticles in Microglia Activation

MR White - 2022 - vtechworks.lib.vt.edu
Traumatic brain injury (TBI) is a major medical concern that has demonstrated to be
particularly challenging to treat because of the disparity amongst injury modes and …