Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Initially a condition that received limited recognition and whose clinical impact was
controversial, non-alcoholic steatohepatitis (NASH) has become a leading cause of chronic …

The increasing epidemic of obesity worldwide is linked to serious health effects, including
increased prevalence of type 2 diabetes mellitus, cardiovascular disease and nonalcoholic …

Osteoarthritis (OA), characterized by joint malfunction and chronic disability, is the most
common form of arthritis. Clinical and animal experiments reveal that age-related OA is …

The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Patients with type 2 diabetes mellitus (T2DM) are at high risk for macrovascular
complications, which represent the major cause of mortality. Despite effective treatment of …

Background: On the 31 December 2019, the World Health Organization (WHO) was
informed of a cluster of cases of pneumonia of unknown origin detected in Wuhan City …

Background & Aims Peroxisome proliferator-activated receptors (PPARs) are essential
regulators of whole-body metabolism, but also modulate inflammation in immune cells …

Metabolic syndrome is defined by a constellation of interconnected physiological,
biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular …

Preterm birth is an increasing worldwide problem. Prematurity is the second most common
cause of death in children under 5 years of age. It is associated with a higher risk of several …