Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

Adiposity and cancer risk: new mechanistic insights from epidemiology

AG Renehan, M Zwahlen, M Egger - Nature Reviews Cancer, 2015 - nature.com
Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for
many common adult cancers. Over the past decade, epidemiological data have shown that …

Associations of weight gain from early to middle adulthood with major health outcomes later in life

Y Zheng, JAE Manson, C Yuan, MH Liang, F Grodstein… - Jama, 2017 - jamanetwork.com
Importance Data describing the effects of weight gain across adulthood on overall health are
important for weight control. Objective To examine the association of weight gain from early …

Obesity as a major risk factor for cancer

G De Pergola, F Silvestris - Journal of obesity, 2013 - Wiley Online Library
The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

World Cancer Research Fund International: Continuous Update Project—systematic literature review and meta-analysis of observational cohort studies on physical …

DSM Chan, L Abar, M Cariolou, N Nanu… - Cancer causes & …, 2019 - Springer
Purpose The purpose of the present study was to systematically review the complex
associations between energy balance-related factors and breast cancer risk, for which …

Adult weight gain and adiposity-related cancers: a dose-response meta-analysis of prospective observational studies

NN Keum, DC Greenwood, DH Lee… - Journal of the …, 2015 - academic.oup.com
Background: Adiposity, measured by body mass index, is implicated in carcinogenesis.
While adult weight gain has diverse advantages over body mass index in measuring …

Obesity and cancer: an update of the global impact

M Arnold, M Leitzmann, H Freisling, F Bray… - Cancer …, 2016 - Elsevier
In view of the growing global obesity epidemic, this paper reviews the relation between
recent trends in body mass index (BMI) and the changing profile of cancer worldwide. By …

Body mass index and breast cancer risk according to postmenopausal estrogen-progestin use and hormone receptor status

MF Munsell, BL Sprague, DA Berry… - Epidemiologic …, 2014 - academic.oup.com
To assess the joint relationships among body mass index, menopausal status, and breast
cancer according to breast cancer subtype and estrogen-progestin medication use, we …

Weight gain after breast cancer diagnosis and all-cause mortality: systematic review and meta-analysis

MC Playdon, MB Bracken, TB Sanft… - Journal of the …, 2015 - academic.oup.com
Background: Overweight and obesity are associated with breast cancer mortality. However,
the relationship between postdiagnosis weight gain and mortality is unclear. We conducted …

The importance of body composition in explaining the overweight paradox in cancer—counterpoint

BJ Caan, EM Cespedes Feliciano, CH Kroenke - Cancer research, 2018 - AACR
Despite a greater risk of cancer associated with higher BMI, overweight (BMI 25–< 30 kg/m2)
and class I obese (BMI 30–< 35 kg/m2) patients often have a paradoxically lower risk of …