Large portions of the thalamus receive strong driving input from cortical layer 5 (L5) neurons
but the role of this important pathway in cortical and thalamic computations is not well …

This review provides an overview of the synaptic dysfunction of neuronal circuits and the
ensuing behavioral alterations caused by mutations in autism spectrum disorder (ASD) …

PACS1 syndrome is a neurodevelopmental disorder (NDD) caused by a recurrent de novo
missense mutation in PACS1 (p. Arg203Trp (PACS1R203W)). The mechanism by which …

Members of the Shank protein family are master scaffolds of the postsynaptic architecture
and mutations within the SHANK genes are causally associated with autism spectrum …

Dysfunction in sodium channels and their ankyrin scaffolding partners have both been
implicated in neurodevelopmental disorders, including autism spectrum disorder (ASD). In …

The dihydropyrimidinase-like (DPYSL) proteins, also designated as the collapsin response
mediators (CRMP) proteins, constitute a family of five cytosolic phosphoproteins abundantly …

The Cooperative Neuron is part of a revolution that is occurring in the sciences of brain and
mind. It explores the new field of cellular psychology, a field built upon the recent discovery …

Abstract Background Neurodevelopmental disorders (NDDs) are a group of disorders
induced by abnormal brain developmental processes. The prefrontal cortex (PFC) plays an …

Pyramidal neurons have a pivotal role in the cognitive capabilities of neocortex. Though they
have been predominantly modeled as integrate-and-fire point processors, many of them …

Autism spectrum disorder (ASD) has recently been linked to neuroinflammation and an
aberrant immune response within the central nervous system. The intricate relationship …