[HTML][HTML] Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way

FSC Sczepanik, ML Grossi, M Casati… - Periodontology …, 2020 - Wiley Online Library
Periodontitis is a highly prevalent disease. As it progresses, it causes serious morbidity in
the form of periodontal abscesses and tooth loss and, in the latter stages, pain. It is also now …

Polydopamine nanoparticles as efficient scavengers for reactive oxygen species in periodontal disease

X Bao, J Zhao, J Sun, M Hu, X Yang - ACS nano, 2018 - ACS Publications
Antioxidative therapy has been considered an efficient strategy for the treatment of a series
of excessive reactive oxygen species (ROS)-triggered diseases, including oxidative-stress …

Targeting endogenous hydrogen peroxide at bone defects promotes bone repair

J Li, F Han, J Ma, H Wang, J Pan… - Advanced Functional …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) plays a critical role in tissue repair, including bone.
Therefore, detecting and regulating ROS is essential for monitoring and facilitating bone …

Electroactive biomaterials for facilitating bone defect repair under pathological conditions

BC Heng, Y Bai, X Li, LW Lim, W Li, Z Ge… - Advanced …, 2023 - Wiley Online Library
Bone degeneration associated with various diseases is increasing due to rapid aging,
sedentary lifestyles, and unhealthy diets. Living bone tissue has bioelectric properties critical …

Garlic (Allium sativum L.) Bioactives and Its Role in Alleviating Oral Pathologies

M Sasi, S Kumar, M Kumar, S Thapa, U Prajapati… - Antioxidants, 2021 - mdpi.com
Garlic (Allium sativa L.) is a bulbous flowering plant belongs to the family of Amaryllidaceae
and is a predominant horticultural crop originating from central Asia. Garlic and its products …

ROS signaling cascades: dual regulations for osteoclast and osteoblast

H Tao, G Ge, X Liang, W Zhang, H Sun… - Acta Biochimica et …, 2020 - academic.oup.com
Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …

Cerium oxide nanozyme attenuates periodontal bone destruction by inhibiting the ROS–NFκB pathway

Y Yu, S Zhao, D Gu, B Zhu, H Liu, W Wu, J Wu, H Wei… - Nanoscale, 2022 - pubs.rsc.org
Periodontitis, an inflammatory disease of oxidative stress, occurs due to excess reactive
oxygen species (ROS) contributing to cell and tissue damage which in turn leads to alveolar …

Oxygen self‐sufficient nanoplatform for enhanced and selective antibacterial photodynamic therapy against anaerobe‐induced periodontal disease

X Sun, J Sun, Y Sun, C Li, J Fang… - Advanced Functional …, 2021 - Wiley Online Library
The hypoxic microenvironment, continuous oxygen consumption, and poor excitation light
penetration depth during antimicrobial photodynamic therapy (aPDT) tremendously hinder …

Mitochondrial DNA in NLRP3 inflammasome activation

Y Qiu, Y Huang, M Chen, Y Yang, X Li… - International …, 2022 - Elsevier
As an intracellular polyprotein complex, the NLRP3 inflammasome is activated by NLRP3
perceiving pathogen-related molecular patterns, damage-related molecular patterns …