Background The hypotension of septic shock is due to systemic vasodilation. On the basis of
a clinical observation, we investigated the possibility that a deficiency in vasopressin …

Background Septic shock is associated with vasopressin deficiency and a hypersensitivity to
its exogenous administration. The goal of the current study was to determine whether short …

The antidiuretic hormone arginine vasopressin is a powerful vasoconstrictor [11.
Vasopressin exerts potent effects on arterial smooth muscle by interacting with a vascular …

Vasopressin has been shown to elicit vasoconstriction in unanaesthetized animals at
plasma concentrations similar to those associated with its renal antidiuretic effect. The …

Background—Hypovolemic shock of marked severity and duration may progress to
cardiovascular collapse unresponsive to volume replacement and drug intervention. On the …

BACKGROUND: Inhibition of angiotensin-converting enzyme (ACE) predisposes patients to
vasodilatory hypotension after cardiopulmonary bypass (CPB). This hypotension has been …

Arginine vasopressin (AVP) is a potent vasopressor and antidiuretic neurohormone.
However, when administered intravenously to humans, AVP causes forearm vasodilation …

Arginine vasopressin (AVP) regulation was studied in 42 patients with severe heart failure
(CHF) and 10 patients without CHF during cardiac catheterization. Plasma AVP levels were …

Objective Hypotension, vasodilation, and vasoplegia are characteristic signs of septic shock.
The vasoconstrictive response to catecholamines typically is reduced. A decreased …

Objective: To determine whether vasopressin could be effective in treating the hypotension
associated with phosphodiesterase III inhibition. Phosphodiesterase III inhibitors are …