Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Dysregulation of the immune system is associated with many pathologies, including
cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in …

Hypoxia is a common hallmark of healthy tissues in physiological states or chronically
inflamed tissues in pathological states. Mammalian cells sense and adapt to hypoxia mainly …

B-cell development is a very orchestrated pathway that involves several molecules, such as
transcription factors, cytokines, microRNAs, and also different cells. All these components …

Simple Summary In this review, we analyze the contribution of the most abundant immune
cell populations in hepatocellular carcinoma (HCC) progression and response to therapy …

Trillions of microorganisms inhabit the mucosal membranes maintaining a symbiotic
relationship with the host's immune system. B cells are key players in this relationship …

B cells, which consist of two well-defined populations: B1 and B2 cells, which can produce
antibodies that are essential for host protection against infections, through virus …

Diffuse large B-cell lymphoma (DLBCL) stands as a formidable challenge in the landscape
of non-Hodgkin's lymphomas. This review illuminates the remarkable strides made in …

Diagnosis of Toxoplasma gondii acute infection was first attempted by detection of specific
IgM antibodies, as for other infectious diseases. However, it was noted that this …

The presented controversial hypothesis is an attempt to reflect on the role of the adaptive
immune response in carcinogenesis. It is a well-known fact that the most of the signaling …