Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …

Diabetes, a chronic physiological dysfunction affecting people of different age groups and
severely impairs the harmony of peoples' normal life worldwide. Despite the availability of …

Introduction Oxidative stress and inflammation are known to play a critical role in ageing and
chronic disease development and could therefore represent important targets for developing …

Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …

Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and
exogenous processes, and their negative effects are neutralized by antioxidant defenses …

Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of 'stress' …

Oxidative stress has been considered as a major hallmark for the pathogenesis and
development of type 2 diabetes mellitus (T2DM), but still it is debatable whether it is a mere …

Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Reactive oxygen species (ROS) and mitochondria play a pivotal role in regulating platelet
functions. Platelet activation determines a drastic change in redox balance and in platelet …

Both oxidative stress and inflammation are enhanced in chronic heart failure. Dysfunction of
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …