Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Risk and protective factors for COVID-19 morbidity, severity, and mortality

J Zhang, X Dong, G Liu, Y Gao - Clinical reviews in allergy & immunology, 2023 - Springer
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become an evolving global …

Characteristics and outcomes of US children and adolescents with multisystem inflammatory syndrome in children (MIS-C) compared with severe acute COVID-19

LR Feldstein, MW Tenforde, KG Friedman, M Newhams… - Jama, 2021 - jamanetwork.com
Importance Refinement of criteria for multisystem inflammatory syndrome in children (MIS-C)
may inform efforts to improve health outcomes. Objective To compare clinical characteristics …

Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: a prospective cohort study

IM Osmanov, E Spiridonova, P Bobkova… - European …, 2022 - Eur Respiratory Soc
Background The long-term sequelae of coronavirus disease 2019 (COVID-19) in children
remain poorly characterised. This study aimed to assess long-term outcomes in children …

[HTML][HTML] Persistent symptoms following SARS-CoV-2 infection amongst children and young people: a meta-analysis of controlled and uncontrolled studies

SA Behnood, R Shafran, SD Bennett, AXD Zhang… - Journal of Infection, 2022 - Elsevier
Background Data on the long-term impact of SARS-CoV-2 infection in children and young
people (CYP) are conflicting. We assessed evidence on long-term post-COVID symptoms in …

Trends in geographic and temporal distribution of US children with multisystem inflammatory syndrome during the COVID-19 pandemic

ED Belay, J Abrams, ME Oster, J Giovanni… - JAMA …, 2021 - jamanetwork.com
Importance Multiple inflammatory syndrome in children (MIS-C) occurs in association with
the COVID-19 pandemic. Objective To describe the clinical characteristics and geographic …

Multisystem inflammatory syndrome in children—initial therapy and outcomes

MBF Son, N Murray, K Friedman… - … England Journal of …, 2021 - Mass Medical Soc
Background The assessment of real-world effectiveness of immunomodulatory medications
for multisystem inflammatory syndrome in children (MIS-C) may guide therapy. Methods We …

[HTML][HTML] Severe COVID-19 infection and pediatric comorbidities: a systematic review and meta-analysis

BK Tsankov, JM Allaire, MA Irvine, AA Lopez… - International Journal of …, 2021 - Elsevier
Objective There is limited information on the severity of COVID-19 infection in children with
comorbidities. We investigated the effects of pediatric comorbidities on COVID-19 severity by …

Factors linked to severe outcomes in multisystem inflammatory syndrome in children (MIS-C) in the USA: a retrospective surveillance study

JY Abrams, ME Oster, SE Godfred-Cato… - The Lancet Child & …, 2021 - thelancet.com
Background Multisystem inflammatory syndrome in children (MIS-C) is a newly identified
and serious health condition associated with SARS-CoV-2 infection. Clinical manifestations …

Case report and systematic review suggest that children may experience similar long‐term effects to adults after clinical COVID‐19

JF Ludvigsson - Acta Paediatrica, 2021 - Wiley Online Library
Aim Persistent symptoms in adults after COVID‐19 are emerging and the term long COVID is
increasingly appearing in the literature. However, paediatric data are scarce. Methods This …