Towards glycan foldamers and programmable assemblies
S Djalali, N Yadav, M Delbianco - Nature Reviews Materials, 2024 - nature.com
Natural biopolymers have inspired the development of synthetic analogues that can adopt
defined conformations and assemble into 3D architectures. These compounds are mainly …
defined conformations and assemble into 3D architectures. These compounds are mainly …
Chemical modification of hyaluronan and their biomedical applications
V Hintze, M Schnabelrauch, S Rother - Frontiers in Chemistry, 2022 - frontiersin.org
Hyaluronan, the extracellular matrix glycosaminoglycan, is an important structural
component of many tissues playing a critical role in a variety of biological contexts. This …
component of many tissues playing a critical role in a variety of biological contexts. This …
Precision native polysaccharides from living polymerization of anhydrosugars
The composition, sequence, length and type of glycosidic linkage of polysaccharides
profoundly affect their biological and physical properties. However, investigation of the …
profoundly affect their biological and physical properties. However, investigation of the …
Promoter‐Controlled Synthesis and Conformational Analysis of Cyclic Mannosides up to a 32‐mer
X Li, C Di Carluccio, H Miao, L Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
Cyclodextrins are widely used as carriers of small molecules for drug delivery owing to their
remarkable host properties and excellent biocompatibility. However, cyclic oligosaccharides …
remarkable host properties and excellent biocompatibility. However, cyclic oligosaccharides …
Chemical synthesis of polysaccharides
S Wang, Y Yang, Q Zhu, GQ Lin, B Yu - Current Opinion in Chemical …, 2022 - Elsevier
Here we summarize the chemical syntheses of glycans containing over 20 monosaccharide
units, with the recent syntheses of ultra-long glycans, including a 92mer arabinogalactan, a …
units, with the recent syntheses of ultra-long glycans, including a 92mer arabinogalactan, a …
Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …
On resin synthesis of sulfated oligosaccharides
T Tyrikos-Ergas, ET Sletten, JY Huang… - Chemical …, 2022 - pubs.rsc.org
Sulfated glycans are involved in many biological processes, making well-defined sulfated
oligosaccharides highly sought molecular probes. These compounds are a considerable …
oligosaccharides highly sought molecular probes. These compounds are a considerable …
Synthetic phosphoethanolamine-modified oligosaccharides reveal the importance of glycan length and substitution in biofilm-inspired assemblies
T Tyrikos-Ergas, S Gim, JY Huang… - Nature …, 2022 - nature.com
Bacterial biofilm matrices are nanocomposites of proteins and polysaccharides with
remarkable mechanical properties. Efforts understanding and tuning the protein component …
remarkable mechanical properties. Efforts understanding and tuning the protein component …
Alternative processes to produce chitin, chitosan, and their oligomers
Sustainable recovery of chitin and its derivatives from shellfish waste will be achieved when
the industrial production of these polymers is achieved with a high control of their molecular …
the industrial production of these polymers is achieved with a high control of their molecular …
Protecting group principles suited to late stage functionalization and global deprotection in oligosaccharide synthesis
Chemical synthesis is a powerful tool to access homogeneous complex glycans, which
relies on protecting group (PG) chemistry. However, the overall efficiency of chemical glycan …
relies on protecting group (PG) chemistry. However, the overall efficiency of chemical glycan …