Recent studies have established that dysregulation of the human immune system and the
reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight …

Common and rare alleles are now being annotated across millions of human genomes, and
omics technologies are increasingly being used to develop health and treatment …

Exercise has shown little success in mitigating bone loss from long‐duration spaceflight. The
first crews of the International Space Station (ISS) used the “interim resistive exercise …

The aim of this investigation was to document the exercise program used by crewmembers
(n= 9; 45±2 yr) while aboard the International Space Station (ISS) for 6 mo and examine its …

The primary goal of this study was to determine the effects of prolonged space flight (∼ 180
days) on the structure and function of slow and fast fibres in human skeletal muscle …

This scoping review aimed to identify current evidence and gaps in the field of long-term
space nutrition. Specifically, the review targeted critical nutritional needs during long-term …

The aim of personalized medicine is to detach from a “one-size fits all approach” and
improve patient health by individualization to achieve the best outcomes in disease …

Concern about the risk of bone loss in astronauts as a result of prolonged exposure to
microgravity prompted the National Aeronautics and Space Administration to convene a …

Humans are generally in standing or sitting positions on Earth during the day. The
musculoskeletal system supports these positions and also allows motion. Gravity acting in …

Homeostasis of bone metabolism is regulated by the central nervous system, and mood
disorders such as anxiety are associated with bone metabolism abnormalities, yet our …