Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro, In Vivo, and In …
SM Hefny, TF El-Moselhy, N El-Din… - Journal of Medicinal …, 2024 - ACS Publications
A dual-targeting approach is predicted to yield better cancer therapy outcomes.
Consequently, a series of coumarin-based thiazoles (5a–h, 6, and 7a–e) were designed and …
Consequently, a series of coumarin-based thiazoles (5a–h, 6, and 7a–e) were designed and …
[HTML][HTML] EGFR as therapeutic target to develop new generation tyrosine kinase inhibitors against breast cancer: A critical review
RM Raju, JA Jeffin, RN Manjunathaiah, A Justin… - Results in …, 2024 - Elsevier
Abstract Epidermal Growth Factor Receptor is a multifunctional receptor and is an important
member of tyrosine kinase family. Investigation on mechanism of tumour progression and its …
member of tyrosine kinase family. Investigation on mechanism of tumour progression and its …
Synthesis, molecular docking, enzyme inhibition and antioxidant potential of new 1H-benzo [d] imidazole-5-carboxamide derivatives
CE Theodore, SBB Prasad, KY Kumar… - Journal of Molecular …, 2024 - Elsevier
The therapeutic potential of benzimidazole has brought them widespread recognition as a
class of heterocyclic compounds having nitrogen-containing rings. In recent years, there has …
class of heterocyclic compounds having nitrogen-containing rings. In recent years, there has …
Synthesis, biological evaluation and molecular docking studies of new pyrimidine derivatives as potent dual EGFR/HDAC inhibitors
G Sivaiah, MS Raghu, SBB Prasad, AM Anusuya… - Journal of Molecular …, 2024 - Elsevier
Pyrimidine scaffolds are an exceptional kind of heterocyclic ring that may be used to create
and develop novel anticancer drugs. As a result, the current work described the design and …
and develop novel anticancer drugs. As a result, the current work described the design and …
Spectroscopic characterization, quantum chemical and molecular docking investigations on methyl indole-3-carboxylate: A potent cervical cancer drug
V Meenakumari, J Mangaiyarkkarasi… - Journal of Molecular …, 2024 - Elsevier
Bioactive indole derivatives had great importance in recent years due to their numerous
biological and pharmaceutical applications. In the present work, the vibrational, electronic …
biological and pharmaceutical applications. In the present work, the vibrational, electronic …
Thiazole derivatives: prospectives and biological applications
U Fathy - Journal of Sulfur Chemistry, 2024 - Taylor & Francis
Thiazole derivatives have long been a hot topic in pharmaceutical research and remain
among the greatest active fields in heterocyclic chemistry. Thiazole derivatives, as one of the …
among the greatest active fields in heterocyclic chemistry. Thiazole derivatives, as one of the …
[HTML][HTML] Biological Activities of Recent Advances in Quinazoline
AG Al-Kaf, RA Al-Robaidi - 2024 - intechopen.com
Quinazolines are important stable heterocyclic compounds of great biological activates.
Naturally, they are found in many plants that are the source of these quinazolines in addition …
Naturally, they are found in many plants that are the source of these quinazolines in addition …
[图书][B] Recent Advances on Quinazoline
AG Al-Kaf - 2024 - books.google.com
This book investigates and identifies novel therapeutic compounds for the treatment of a
range of illnesses. Heterocyclic compounds are a significant class of substances with …
range of illnesses. Heterocyclic compounds are a significant class of substances with …
A Simple and Highly Efficient One-Pot Three-Component Synthesis of Uracil and Thiouracil Based Spiro Chromeno-Pyrimidine-Indolinones and Novel Spiro Pyrano …
M Pasha, A Khanum - Available at SSRN 4705873 - papers.ssrn.com
A novel and efficient synthesis of some important uracil and thiouracil based spiro chromeno-
indolinones and novel spiro pyrano-indolinones from cyclohexa/cyclopenta-1, 3-diketones …
indolinones and novel spiro pyrano-indolinones from cyclohexa/cyclopenta-1, 3-diketones …
[PDF][PDF] Aliabadi, Alireza
A Mohammadi-Farani - ijcce.ac.ir
According to the rising stafisfics of cancer cases, the discovery of novel anficancer drugs is a
crifical issue in current medical research. Besides, drug resistance and the incidence of …
crifical issue in current medical research. Besides, drug resistance and the incidence of …