[PDF][PDF] Functional neuroimaging in psychiatry and the case for failing better

MM Nour, Y Liu, RJ Dolan - Neuron, 2022 - cell.com
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …

[HTML][HTML] The promise of a model-based psychiatry: building computational models of mental ill health

TU Hauser, V Skvortsova, M De Choudhury… - The Lancet Digital …, 2022 - thelancet.com
Computational models have great potential to revolutionise psychiatry research and clinical
practice. These models are now used across multiple subfields, including computational …

Coupling of pupil-and neuronal population dynamics reveals diverse influences of arousal on cortical processing

T Pfeffer, C Keitel, DS Kluger, A Keitel, A Russmann… - elife, 2022 - elifesciences.org
Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …

Aberrant maturation and connectivity of prefrontal cortex in schizophrenia—contribution of NMDA receptor development and hypofunction

WJ Gao, SS Yang, NR Mack, LA Chamberlin - Molecular psychiatry, 2022 - nature.com
The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from
its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level …

[HTML][HTML] A diversity of intrinsic timescales underlie neural computations

SE Cavanagh, LT Hunt, SW Kennerley - Frontiers in Neural Circuits, 2020 - frontiersin.org
Neural processing occurs across a range of temporal scales. To facilitate this, the brain uses
fast-changing representations reflecting momentary sensory input alongside more …

Premature commitment to uncertain decisions during human NMDA receptor hypofunction

A Salvador, LH Arnal, F Vinckier, P Domenech… - Nature …, 2022 - nature.com
Making accurate decisions based on unreliable sensory evidence requires cognitive
inference. Dysfunction of n-methyl-d-aspartate (NMDA) receptors impairs the integration of …

Towards biologically constrained attractor models of schizophrenia

H Stein, J Barbosa, A Compte - Current opinion in neurobiology, 2021 - Elsevier
Alterations in neuromodulation or synaptic transmission in biophysical attractor network
models, as proposed by the dominant dopaminergic and glutamatergic theories of …

Frontal circuit specialisations for decision making

LT Hunt - European Journal of Neuroscience, 2021 - Wiley Online Library
There is widespread consensus that distributed circuits across prefrontal and anterior
cingulate cortex (PFC/ACC) are critical for reward‐based decision making. The circuit …

The neurochemistry of hypnotic suggestion

DJ Acunzo, DA Oakley, DB Terhune - American Journal of Clinical …, 2021 - Taylor & Francis
ABSTRACT A diverse array of studies has been devoted to understanding the
neurochemical systems supporting responsiveness to hypnotic suggestions, with …

Overview on cognitive impairment in psychotic disorders: From impaired microcircuits to dysconnectivity

L Mana, M Schwartz-Pallejà, M Vila-Vidal… - Schizophrenia Research, 2024 - Elsevier
Schizophrenia's cognitive deficits, often overshadowed by positive symptoms, significantly
contribute to the disorder's morbidity. Increasing attention highlights these deficits as …