[PDF][PDF] Functional neuroimaging in psychiatry and the case for failing better
Psychiatric disorders encompass complex aberrations of cognition and affect and are
among the most debilitating and poorly understood of any medical condition. Current …
among the most debilitating and poorly understood of any medical condition. Current …
[HTML][HTML] The promise of a model-based psychiatry: building computational models of mental ill health
Computational models have great potential to revolutionise psychiatry research and clinical
practice. These models are now used across multiple subfields, including computational …
practice. These models are now used across multiple subfields, including computational …
Coupling of pupil-and neuronal population dynamics reveals diverse influences of arousal on cortical processing
Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …
shape cortical state, with profound consequences for information processing. Yet, how …
Aberrant maturation and connectivity of prefrontal cortex in schizophrenia—contribution of NMDA receptor development and hypofunction
The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from
its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level …
its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level …
[HTML][HTML] A diversity of intrinsic timescales underlie neural computations
SE Cavanagh, LT Hunt, SW Kennerley - Frontiers in Neural Circuits, 2020 - frontiersin.org
Neural processing occurs across a range of temporal scales. To facilitate this, the brain uses
fast-changing representations reflecting momentary sensory input alongside more …
fast-changing representations reflecting momentary sensory input alongside more …
Premature commitment to uncertain decisions during human NMDA receptor hypofunction
Making accurate decisions based on unreliable sensory evidence requires cognitive
inference. Dysfunction of n-methyl-d-aspartate (NMDA) receptors impairs the integration of …
inference. Dysfunction of n-methyl-d-aspartate (NMDA) receptors impairs the integration of …
Towards biologically constrained attractor models of schizophrenia
Alterations in neuromodulation or synaptic transmission in biophysical attractor network
models, as proposed by the dominant dopaminergic and glutamatergic theories of …
models, as proposed by the dominant dopaminergic and glutamatergic theories of …
Frontal circuit specialisations for decision making
LT Hunt - European Journal of Neuroscience, 2021 - Wiley Online Library
There is widespread consensus that distributed circuits across prefrontal and anterior
cingulate cortex (PFC/ACC) are critical for reward‐based decision making. The circuit …
cingulate cortex (PFC/ACC) are critical for reward‐based decision making. The circuit …
The neurochemistry of hypnotic suggestion
DJ Acunzo, DA Oakley, DB Terhune - American Journal of Clinical …, 2021 - Taylor & Francis
ABSTRACT A diverse array of studies has been devoted to understanding the
neurochemical systems supporting responsiveness to hypnotic suggestions, with …
neurochemical systems supporting responsiveness to hypnotic suggestions, with …
Overview on cognitive impairment in psychotic disorders: From impaired microcircuits to dysconnectivity
L Mana, M Schwartz-Pallejà, M Vila-Vidal… - Schizophrenia Research, 2024 - Elsevier
Schizophrenia's cognitive deficits, often overshadowed by positive symptoms, significantly
contribute to the disorder's morbidity. Increasing attention highlights these deficits as …
contribute to the disorder's morbidity. Increasing attention highlights these deficits as …