[PDF][PDF] Clinical and biological significance of CD34 expression in acute leukemia

G Basso, F Lanza, A Orfao, S Moretti… - Journal of biological …, 2001 - researchgate.net
© by Wichtig Editore, 2001 0393-974X/068-011 $05.50 a significant increase in the number
of positive cells, due to various reasons, such as occurrence of nonspecific cross-reactivity …

The clinical significance of CD34 expression in response to therapy of patients with acute myeloid leukemia: an overview of 2483 patients from 22 studies

Y Kanda, T Hamaki, R Yamamoto… - … Journal of the …, 2000 - Wiley Online Library
BACKGROUND Although many studies have been performed to evaluate the prognostic
significance of CD34 expression in acute myeloid leukemia (AML), the findings have been …

Expression of AC133, a novel hematopoietic precursor antigen, on acute myeloid leukemia cells

PA Horn, H Tesch, P Staib, D Kube… - Blood, The Journal …, 1999 - ashpublications.org
In a recent issue of BLOOD, Yin et al1 reported the production of AC133, a monoclonal
antibody (MoAb) that binds to a novel cell surface antigen present on a CD34 (bright) subset …

Expression of costimulatory molecule B7-H3 and its prognostic implications in human acute leukemia

Y Hu, X Lv, Y Wu, J Xu, L Wang, W Chen, W Zhang… - …, 2015 - Taylor & Francis
Objectives This study focused on the expression pattern and clinical significance of B7-H3
expression in human acute leukemia. Methods We systematically analyzed 134 patients …

Absence of leukaemic CD34+ cells in acute myeloid leukaemia is of high prognostic value: a longstanding controversy deciphered

W Zeijlemaker, A Kelder, R Wouters… - British journal of …, 2015 - Wiley Online Library
Primary resistance and relapses after initial successful treatment are common in acute
myeloid leukaemia and therefore outcome remains poor. More accurate risk group …

Differences between the CD34+ and CD34-blast compartments in apoptosis resistance in acute myeloid leukemia

A van Stijn, MA van der Pol, A Kok, PM Bontje… - …, 2003 - haematologica.org
BACKGROUND AND OBJECTIVES: Altered expression of members of the Bcl-2 family might
account for the observed apoptosis resistance to chemotherapy in acute myeloid leukemia …

Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation …

C Wuchter, L Karawajew, V Ruppert, T Büchner… - Leukemia, 1999 - nature.com
Resistance to chemotherapy-induced apoptosis and a multidrug-resistance (MDR)
phenotype, mainly mediated by P-glycoprotein (P-gp), contribute to chemotherapy failure in …

Cytogenetic findings in adult de novo acute myeloid leukaemia. A population‐based study of 303/337 patients

BS Preiss, GB Kerndrup, KG Schmidt… - British journal of …, 2003 - Wiley Online Library
During a 10‐year period (1992–2001) in the region of Southern Denmark, 337 patients aged
15 years or older (range 16–93 years, median 67 years) were diagnosed with acute myeloid …

Integrative meta-analysis of differential gene expression in acute myeloid leukemia

BG Miller, JA Stamatoyannopoulos - PLoS One, 2010 - journals.plos.org
Background Acute myeloid leukemia (AML) is a heterogeneous disease with an overall poor
prognosis. Gene expression profiling studies of patients with AML has provided key insights …

Different expression of adhesion molecules on CD34+ cells in AML and B‐lineage ALL and their normal bone marrow counterparts

M De Waele, W Renmans, K Jochmans… - European journal of …, 1999 - Wiley Online Library
The expression of adhesion molecules on CD34+ cells in acute myeloid leukemia (AML)
and B‐lineage acute lymphoblastic leukemia (B‐lineage ALL) was compared with that on …