[HTML][HTML] Regulation of gram-positive conjugation

V Kohler, W Keller, E Grohmann - Frontiers in microbiology, 2019 - frontiersin.org
Type IV Secretion Systems (T4SSs) are membrane-spanning multiprotein complexes
dedicated to protein secretion or conjugative DNA transport (conjugation systems) in …

[HTML][HTML] Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20

WJJ Meijer, DR Boer, S Ares, C Alfonso… - Frontiers in Molecular …, 2021 - frontiersin.org
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of
antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from …

[HTML][HTML] Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch

X Fang, Q Liu, C Bohrer, Z Hensel, W Han… - Nature …, 2018 - nature.com
Bistable switches are common gene regulatory motifs directing two mutually exclusive cell
fates. Theoretical studies suggest that bistable switches are sufficient to encode more than …

[HTML][HTML] Discovery of a new family of relaxases in Firmicutes bacteria

G Ramachandran, A Miguel-Arribas, D Abia… - PLoS …, 2017 - journals.plos.org
Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which
are widespread in environmental bacteria, can be transferred to pathogenic bacteria via …

Mechanisms of peptide sex pheromone regulation of conjugation in Enterococcus faecalis

Y Chen, A Bandyopadhyay, BK Kozlowicz… - …, 2017 - Wiley Online Library
In many gram positive bacteria, horizontal transfer and virulence are regulated by peptide‐
mediated cell‐cell signaling. The heptapeptide cCF 10 (C) activates conjugative transfer of …

[HTML][HTML] Surface Exclusion Revisited: Function Related to Differential Expression of the Surface Exclusion System of Bacillus subtilis Plasmid pLS20

C Gago-Córdoba, J Val-Calvo… - Frontiers in …, 2019 - frontiersin.org
During conjugation a genetic element is transferred from a bacterial donor to a recipient cell
via a connecting channel. It is the major route responsible for the spread of antibiotic …

pLS20 is the archetype of a new family of conjugative plasmids harboured by Bacillus species

J Val-Calvo, A Miguel-Arribas, D Abia… - NAR Genomics and …, 2021 - academic.oup.com
Conjugation plays important roles in genome plasticity, adaptation and evolution but is also
the major horizontal gene-transfer route responsible for spreading toxin, virulence and …

Mechanisms of conjugative transfer and type IV secretion-mediated effector transport in gram-positive bacteria

E Grohmann, W Keller, G Muth - Type IV Secretion in Gram-Negative and …, 2017 - Springer
Conjugative DNA transfer is the most important means to transfer antibiotic resistance genes
and virulence determinants encoded by plasmids, integrative conjugative elements (ICE) …

[HTML][HTML] Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling

A Tsigkinopoulou, E Takano… - PLoS computational …, 2020 - journals.plos.org
Antibiotic production is coordinated in the Streptomyces coelicolor population through the
use of diffusible signaling molecules of the γ-butyrolactone (GBL) family. The GBL regulatory …

A novel bipartite antitermination system widespread in conjugative elements of Gram-positive bacteria

A Miguel-Arribas, J Val-Calvo… - Nucleic acids …, 2021 - academic.oup.com
Transcriptional regulation allows adaptive and coordinated gene expression, and is
essential for life. Processive antitermination systems alter the transcription elongation …