Introduction: Curcumin has been extensively studied for its anti-cancer properties. While a
diverse array of in vitro and preclinical research support the prospect of curcumin use as an …

Abstract P‐glycoprotein (P‐gp) is a transporter protein that is come under the ATP binding
cassette family of proteins. It is situated on the surface of the intestine epithelium, where P …

Proteolysis-targeting chimeras (PROTACs) are a promising new class of drugs that
selectively degrade cellular proteins of interest. PROTACs that target oncogene products are …

Cannabis is a complex mixture of hundreds of bioactive molecules. This provides the
potential for pharmacological interactions between cannabis constituents, a phenomenon …

Drugs that are already clinically approved or experimentally tested for conditions other than
cancer, but are found to possess previously unrecognized cytotoxicity towards malignant …

P-Glycoprotein (P-gp) is a transmembrane protein belonging to the ATP binding cassette
superfamily of transporters, and it is a xenobiotic efflux pump that limits intracellular drug …

Abstract P-glycoprotein (P-gp) is a drug transporter that effluxes chemotherapeutic drugs
and is implicated in the development of resistance of cancer cells to chemotherapeutic …

To develop a novel intestinal drug absorption system using intestinal epithelial cells derived
from human induced pluripotent stem (iPS) cells, the cells must possess sufficient …

The ABCB1 transporter also known as P-glycoprotein (P-gp) is a transmembrane protein
belonging to the ATP binding cassette super-family of transporters; it is a xenobiotic efflux …

The ATP-binding cassette (ABC) transporters play a key role in drug pharmacokinetics.
These membrane transporters expressed within physiological barriers can be a source of …