Because of the abnormal vasculature, most growing solid tumors contain regions that
experience either acute or chronic hypoxia. However, tumor cells can maintain a high …

Hypoxia in solid tumors is an important predictor of treatment resistance and poor clinical
outcome. The significance of hypoxia in the development of resistance to radiotherapy has …

The blood–brain barrier (BBB) is a complex vascular structure consisting of microvascular
endothelial cells that line the vessel wall, astrocyte end‐feet, pericytes, as well as the basal …

As demonstrated by preclinical and clinical studies, it is often difficult to eradicate tumors,
particularly those that are deep-located, with photothermal therapy (PTT) alone because of …

Abstract Background and Aims Poor response to ionizing radiation (IR) due to resistance
remains a clinical challenge. Altered metabolism represents a defining characteristic of …

Plasmonic nanoparticles and their assemblies have been widely used in biosensing, optical
imaging, and biomedicine over the past few decades. Especially in the field of radiotherapy …

Background Hypoxia induces the epithelial-mesenchymal transition, EMT, to promote
cancer metastasis. In addition to transcriptional regulation mediated by hypoxia-inducible …

Dietary interventions such as intermittent fasting (IF) have emerged as an attractive strategy
for cancer therapies; therefore, understanding the underlying molecular mechanisms is …

Purpose: Cancer is a multigene disease which arises as a result of mutational and
epigenetic changes coupled with activation of complex signaling networks. The use of …

Simple Summary Autophagy is a self-eating mechanism that is involved in the degradation
of organelles and cellular materials. It is initiated by intracellular and extracellular stress …