The function of the right ventricle determines the fate of patients with pulmonary
hypertension. Since right heart failure is the consequence of increased afterload, a full …

Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …

Right ventricular pressure-volume (PV) analysis characterizes ventricular systolic and
diastolic properties independent of loading conditions like volume status and afterload …

Objective Prognosis in pulmonary hypertension (PH) is largely determined by RV function.
However, uncertainty remains about what metrics of RV function might be most clinically …

Pulmonary arterial hypertension (PAH) is a right heart failure syndrome. In early-stage PAH,
the right ventricle tends to remain adapted to afterload with increased contractility and little …

Right ventricular (RV) diastolic stiffness is increased in pulmonary arterial hypertension
(PAH) patients. We investigated whether RV diastolic stiffness is associated with clinical …

Rationale: Exercise tolerance is decreased in patients with pulmonary hypertension (PH). It
is unknown whether exercise intolerance in PH coincides with an impaired rest-to-exercise …

BACKGROUND: Even after years of stable response to therapy, patients with idiopathic
pulmonary arterial hypertension (IPAH) may show an unexpected clinical deterioration due …

Right ventricular (RV) function is a major determinant of the symptomatology and outcome in
pulmonary hypertension. The normal RV is a thin-walled flow generator able to …

Rationale: Pulmonary arterial hypertension (PAH) is a medically incurable disease resulting
in death from right ventricular (RV) failure. Both pulmonary vascular and RV remodeling are …