[HTML][HTML] Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases

J Bai, Y Zhang, C Tang, Y Hou, X Ai, X Chen… - Biomedicine & …, 2021 - Elsevier
Gallic acid (GA), also known as 3, 4, 5-trihydroxybenzoic acid, is a natural secondary
metabolite and widely isolated from various fruits, plants and nuts. In recent years, GA has …

[HTML][HTML] TLR agonists as vaccine adjuvants targeting cancer and infectious diseases

M Luchner, S Reinke, A Milicic - Pharmaceutics, 2021 - mdpi.com
Modern vaccines have largely shifted from using whole, killed or attenuated pathogens to
being based on subunit components. Since this diminishes immunogenicity, vaccine …

[HTML][HTML] Transgenic mouse models of Alzheimer's disease: An integrative analysis

R Sanchez-Varo, M Mejias-Ortega… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) constitutes the most prominent form of dementia among elderly
individuals worldwide. Disease modeling using murine transgenic mice was first initiated …

Protection against Alzheimer's disease by luteolin: Role of brain glucose regulation, anti‐inflammatory activity, and the gut microbiota‐liver‐brain axis

JW Daily, S Kang, S Park - Biofactors, 2021 - Wiley Online Library
Luteolin is a widely distributed flavone herbs and vegetables. It has anti‐oxidant and anti‐
inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity …

[HTML][HTML] Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease

J Lake, C Warly Solsberg, JJ Kim, J Acosta-Uribe… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) of Alzheimer's disease are predominantly carried
out in European ancestry individuals despite the known variation in genetic architecture and …

[HTML][HTML] Impact of Microbiome–Brain Communication on Neuroinflammation and Neurodegeneration

I Stolzer, E Scherer, P Süß, V Rothhammer… - International Journal of …, 2023 - mdpi.com
The gut microbiome plays a pivotal role in maintaining human health, with numerous studies
demonstrating that alterations in microbial compositions can significantly affect the …

[HTML][HTML] Microglia in Alzheimer's disease in the context of tau pathology

JR Perea, M Bolós, J Avila - Biomolecules, 2020 - mdpi.com
Microglia are the cells that comprise the innate immune system in the brain. First described
more than a century ago, these cells were initially assigned a secondary role in the central …

[HTML][HTML] Pathogenesis of (smoking-related) non-communicable diseases—Evidence for a common underlying pathophysiological pattern

W Kopp - Frontiers in Physiology, 2022 - frontiersin.org
Non-communicable diseases, like diabetes, cardiovascular diseases, cancer, stroke, chronic
obstructive pulmonary disease, osteoporosis, arthritis, Alzheimer's disease and other more …

Nao Tan Qing ameliorates Alzheimer's disease-like pathology by regulating glycolipid metabolism and neuroinflammation: a network pharmacology analysis and …

Q Li, C Jia, H Wu, Y Liao, K Yang, S Li, J Zhang… - Pharmacological …, 2022 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline and currently there are no available treatments. Alongside the …

[HTML][HTML] Biological potential, gastrointestinal digestion, absorption, and bioavailability of algae-derived compounds with neuroprotective activity: A comprehensive …

B Martins, M Vieira, C Delerue-Matos, C Grosso… - Marine Drugs, 2022 - mdpi.com
Currently, there is no known cure for neurodegenerative disease. However, the available
therapies aim to manage some of the symptoms of the disease. Human neurodegenerative …