[HTML][HTML] Polysaccharides as antioxidants and prooxidants in managing the double-edged sword of reactive oxygen species

FS Zeng, YF Yao, LF Wang, WJ Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Polysaccharides, a class of naturally occurring carbohydrates, were widely presented in
animals, plants, and microorganisms. Recently, health benefits of polysaccharides have …

Advances in polysaccharides of natural source of the anti-Alzheimer's disease effect and mechanism

Z Zhang, S Wang, H Tan, P Yang, Y Li, L Xu… - Carbohydrate …, 2022 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disorder. The pathology is
characterized by the generation of amyloid plaques and neuronal fiber tangles in the brain …

Oral administration of resveratrol-selenium-peptide nanocomposites alleviates Alzheimer's disease-like pathogenesis by inhibiting Aβ aggregation and regulating gut …

C Li, N Wang, G Zheng, L Yang - ACS Applied Materials & …, 2021 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disease associated with amyloid-β (Aβ)
deposition, leading to neurotoxicity (oxidative stress and neuroinflammation) and gut …

In-depth investigation of the mechanisms of Schisandra chinensis polysaccharide mitigating Alzheimer's disease rat via gut microbiota and feces metabolomics

J Fu, J Li, Y Sun, S Liu, F Song, Z Liu - International Journal of Biological …, 2023 - Elsevier
Schisandra chinensis (S. chinensis) is an herbal medicine used for the treatment of
Alzheimer's disease (AD). The purified polysaccharide fraction, namely SCP2, was …

Angelica polysaccharide ameliorates memory impairment in Alzheimer's disease rat through activating BDNF/TrkB/CREB pathway

Q Du, X Zhu, J Si - Experimental Biology and Medicine, 2020 - journals.sagepub.com
This study aimed to investigate the effect of Angelica sinensis polysaccharides (ASP) on
Alzheimer's disease (AD) and its underlying mechanisms. In our study, we build the AD …

[HTML][HTML] Gut microbiota and its metabolites: bridge of dietary nutrients and Alzheimer's disease

G Zhu, J Zhao, H Zhang, G Wang, W Chen - Advances in Nutrition, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
cognitive impairment and neuroinflammation. Recent research has revealed the crucial role …

An integrated study on the comprehensive mechanism of Schisandra chinensis polysaccharides mitigating Alzheimer's disease in rats using a UPLC-Q-TOF-MS …

J Fu, J Li, Y Sun, S Liu, F Song, Z Liu - Food & Function, 2023 - pubs.rsc.org
As a well-known traditional Chinese medicine and functional food, Schisandra chinensis (S.
chinensis) has been proved to possess excellent neuroprotective effects, and particularly the …

An update review of extraction, purification, structural features, bioactivities, and applications of Schisandra chinensis polysaccharides

F Luan, J Zou, X Zhang, J Zeng, X Peng, R Li… - International Journal of …, 2024 - Elsevier
Schisandra chinensis, as a famous medicinal and food homologous plant, has a long history
of medicinal and dietary therapy. It has the functions of nourishing the kidney, calming the …

Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury

J Zhang, WH Zhang, C Morisseau, M Zhang… - Journal of Hazardous …, 2023 - Elsevier
Air pollution represented by particulate matter 2.5 (PM2. 5) is closely related to diseases of
the respiratory system. Although the understanding of its mechanism is limited, pulmonary …

Mechanism of Huang-lian-Jie-du decoction and its effective fraction in alleviating acute ulcerative colitis in mice: Regulating arachidonic acid metabolism and …

Z Yuan, L Yang, X Zhang, P Ji, Y Hua, Y Wei - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Huang-lian-Jie-du decoction (HLJDD) is a
traditional Chinese medicine prescription for clearing away heat, purging fire and …