Introduction Prevention or treatment for acoustic injury has been met with many translational
challenges, resulting in the absence of FDA-approved interventions. Localized hypothermia …

Auditory neuropathy spectrum disorder (ANSD) associated with mutations of the OTOF gene
is one of the common types of sensorineural hearing loss of a hereditary nature. Due to its …

Since next-generation sequencing (NGS) has become widely available, large gene panels
containing up to several hundred genes can be sequenced cost-efficiently. However, the …

The loss of auditory hair cell in mammals including humans results in permanent hearing
impairment, as they lack the inherent capacity for regeneration. In contrast, the lower …

Noise-induced hearing loss (NIHL) is an acquired form of sensorineural hearing loss
associated with cochlear trauma in response to acoustic over-stimulation. NIHL may present …