Pancreatic cancer is an increasingly common cause of cancer mortality with a tight
correspondence between disease mortality and incidence. Furthermore, it is usually …

Abstract N 6-methyladenosine (m 6 A) is the most abundant mRNA modification and is
catalyzed by the methyltransferase complex, in which methyltransferase-like 3 (METTL3) is …

Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The
uptake and metabolism of amino acids are aberrantly upregulated in many cancers that …

Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …

Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC),
ranks the fourth leading cause of cancer-related deaths in the western world. While the …

Pancreatic ductal adenocarcinoma is most frequently detected at an advanced stage. Such
late detection restricts treatment options and contributes to a dismal 5-year survival rate of 3 …

This review aims to summarize the latest knowledge on factors, diagnosis, and treatment of
pancreatic cancer, and aims to promote further research on this under-studied malignant …

Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less
than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor …

Liver and pancreatic tumors are among the third leading causes of cancer-associated death
worldwide. In addition to poor prognosis, both cancer types are diagnosed at advanced and …