[HTML][HTML] Dyspnea in COPD: new mechanistic insights and management implications

DE O'Donnell, KM Milne, MD James, JP de Torres… - Advances in …, 2020 - Springer
Dyspnea is the most common symptom experienced by patients with chronic obstructive
pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary …

Dyspnoea: a multidimensional and multidisciplinary approach

L Laviolette, P Laveneziana - European Respiratory Journal, 2014 - Eur Respiratory Soc
Dyspnoea is a debilitating symptom that affects quality of life, exercise tolerance and
mortality in various disease conditions/states. In patients with chronic obstructive pulmonary …

Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease–2007 update

DE O'donnell, S Aaron, J Bourbeau… - Canadian …, 2007 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major respiratory illness in Canada that
is both preventable and treatable. Our understanding of the pathophysiology of this complex …

Pathogenesis of hyperinflation in chronic obstructive pulmonary disease

P Gagnon, JA Guenette, D Langer… - … journal of chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable lung disease
characterized by airflow limitation that is not fully reversible. In a significant proportion of …

Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable

DE O'Donnell, RB Banzett… - Proceedings of the …, 2007 - atsjournals.org
Effective management of dyspnea in chronic obstructive pulmonary disease (COPD)
requires a clearer understanding of its underlying mechanisms. This roundtable reviews …

COPD as a lung disease with systemic consequences–clinical impact, mechanisms, and potential for early intervention

M Decramer, S Rennard, T Troosters… - COPD: Journal of …, 2008 - Taylor & Francis
The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the
development of systemic consequences and co-morbidities. These may be major features in …

[HTML][HTML] Pulmonary function testing in COPD: looking beyond the curtain of FEV1

S Kakavas, OS Kotsiou, F Perlikos, M Mermiri… - NPJ primary care …, 2021 - nature.com
Chronic obstructive pulmonary disease (COPD) management remains challenging due to
the high heterogeneity of clinical symptoms and the complex pathophysiological basis of the …

Inspiratory capacity during exercise: measurement, analysis, and interpretation

JA Guenette, RC Chin, JM Cory, KA Webb… - Pulmonary …, 2013 - Wiley Online Library
Cardiopulmonary exercise testing (CPET) is an established method for evaluating dyspnea
and ventilatory abnormalities. Ventilatory reserve is typically assessed as the ratio of peak …

Mechanisms of activity-related dyspnea in pulmonary diseases

DE O'Donnell, J Ora, KA Webb, P Laveneziana… - Respiratory physiology …, 2009 - Elsevier
Progressive activity-related dyspnea dominates the clinical presentation of patients afflicted
by chronic obstructive and restrictive lung diseases. This symptom invariably leads to activity …

Fixed-intensity exercise tests to measure exertional dyspnoea in chronic heart and lung populations: a systematic review

T Palmer, SJ Obst, CR Aitken, J Walsh… - European …, 2023 - Eur Respiratory Soc
Introduction Exertional dyspnoea is the primary diagnostic symptom for chronic
cardiopulmonary disease populations. Whilst a number of exercise tests are used, there …