The extracellular matrix in ischemic and nonischemic heart failure
NG Frangogiannis - Circulation research, 2019 - Am Heart Assoc
The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …
by providing structural support, but also by facilitating force transmission, and by transducing …
The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease
G Burgstaller, B Oehrle, M Gerckens… - European …, 2017 - Eur Respiratory Soc
The pulmonary extracellular matrix (ECM) determines the tissue architecture of the lung, and
provides mechanical stability and elastic recoil, which are essential for physiological lung …
provides mechanical stability and elastic recoil, which are essential for physiological lung …
[HTML][HTML] The extracellular matrix: Tools and insights for the “omics” era
The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
provides mechanical and chemical cues that orchestrate cellular and tissue organization …
Extracellular matrix remodeling and cardiac fibrosis
L Li, Q Zhao, W Kong - Matrix biology, 2018 - Elsevier
Cardiac fibrosis, characterized by excessive deposition of extracellular matrix (ECM)
proteins in the myocardium, distorts the architecture of the myocardium, facilitates the …
proteins in the myocardium, distorts the architecture of the myocardium, facilitates the …
Cardiovascular consequences of metabolic syndrome
The metabolic syndrome (MetS) is defined as the concurrence of obesity-associated
cardiovascular risk factors including abdominal obesity, impaired glucose tolerance …
cardiovascular risk factors including abdominal obesity, impaired glucose tolerance …
Matrix metalloproteinase-9: Many shades of function in cardiovascular disease
A Yabluchanskiy, Y Ma, RP Iyer, ME Hall… - …, 2013 - journals.physiology.org
Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …
Matrix metalloproteinases in myocardial infarction and heart failure
KY DeLeon-Pennell, CA Meschiari, M Jung… - Progress in molecular …, 2017 - Elsevier
Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …
year in the United States. In addition, heart failure accounts for 37% of health care spending …
HDAC inhibition reverses preexisting diastolic dysfunction and blocks covert extracellular matrix remodeling
Background: Diastolic dysfunction (DD) is associated with the development of heart failure
and contributes to the pathogenesis of other cardiac maladies, including atrial fibrillation …
and contributes to the pathogenesis of other cardiac maladies, including atrial fibrillation …
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
Aims A better understanding of the pathways that regulate regeneration of the coronary
vasculature is of fundamental importance for the advancement of strategies to treat patients …
vasculature is of fundamental importance for the advancement of strategies to treat patients …
Native T1 mapping in differentiation of normal myocardium from diffuse disease in hypertrophic and dilated cardiomyopathy
Objectives: The aim of this study was to examine the value of native and post-contrast T1
relaxation in the differentiation between healthy and diffusely diseased myocardium in 2 …
relaxation in the differentiation between healthy and diffusely diseased myocardium in 2 …