Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

This tutorial review covers the recent advances made in the study of gold complexes
containing N-heterocyclic carbene ligands with biological properties. The great stability …

Complexes of metals with N-heterocyclic carbene ligands (M/NHC) are typically considered
the systems of choice in homogeneous catalysis due to their stable metal–ligand framework …

A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

Herein, we report the synthesis and the multiple anti-tumor properties of new gold and silver
carbene complexes. The chemical modifications, grounded on our previous studies, led us …

A series of four new mononuclear cationic gold (I) complexes containing nitrogen
functionalized N-heterocyclic carbenes (NHCs) was synthesized and fully characterized by …

Two gold (III) complexes of isoquinoline derivatives:[Au (L 1) Cl 2](Au1) and [Au (L 2) Cl
2](Au2) have been prepared and characterized. Au1 and Au2 exhibited greater cytotoxicity …

Metal complexes based on N‐heterocyclic carbene (NHC) ligands have emerged as
promising broad‐spectrum antitumor agents in bioorganometallic medicinal chemistry. In …

The synthesis and characterization of a novel macrocyclic Au (III) N-heterocyclic carbene
(NHC) imidazolyl complex, a novel macrocyclic tetra-NHC benzimidazole ligand, and the …

A series of gold (I) and gold (III) complexes with N‐heterocyclic carbene ligands
functionalized with a pendant thioether group (NHC‐SR) was synthesized with …