Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds
HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …
[HTML][HTML] The long and short non-coding RNAs modulating EZH2 signaling in cancer
S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …
encoding proteins. However, they participate in developmental and biological processes …
[HTML][HTML] Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention
S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …
[HTML][HTML] New insight towards development of paclitaxel and docetaxel resistance in cancer cells: EMT as a novel molecular mechanism and therapeutic possibilities
Epithelial-to-mesenchymal transition (EMT) mechanism is responsible for metastasis and
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …
migration of cancer cells to neighboring cells and tissues. Morphologically, epithelial cells …
[HTML][HTML] Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression
M Ashrafizadeh, S Mirzaei, MH Gholami… - Carbohydrate …, 2021 - Elsevier
An important motivation for the use of nanomaterials and nanoarchitectures in cancer
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …
NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …
[HTML][HTML] The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers
I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …
expression by blocking translation or inducing degradation of specific gene transcripts. The …
[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
[HTML][HTML] Cytoskeletal dynamics in epithelial-mesenchymal transition: insights into therapeutic targets for cancer metastasis
A Datta, S Deng, V Gopal, KCH Yap, CE Halim, ML Lye… - Cancers, 2021 - mdpi.com
Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …
The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …