Ethical issues associated with prenatal screening using non‐invasive prenatal testing for sex chromosome aneuploidy
Prenatal screening for sex chromosome aneuploidies (SCAs) is increasingly available
through expanded non‐invasive prenatal testing (NIPT). NIPT for SCAs raises complex …
through expanded non‐invasive prenatal testing (NIPT). NIPT for SCAs raises complex …
[PDF][PDF] The accuracy of cell-free DNA screening for fetal segmental copy number variants: A systematic review and meta-analysis
YC Raymond, ML Acreman, S Bussolaro… - … journal of obstetrics …, 2023 - aura.abdn.ac.uk
Background: The performance of cell-free DNA (cfDNA) screening for microscopic copy
number variants (CNVs) is unclear. Objectives: This was a systematic review and meta …
number variants (CNVs) is unclear. Objectives: This was a systematic review and meta …
[HTML][HTML] A critical evaluation of validation and clinical experience studies in non-invasive prenatal testing for trisomies 21, 18, and 13 and monosomy X
Z Demko, B Prigmore, P Benn - Journal of Clinical Medicine, 2022 - mdpi.com
Non-invasive prenatal testing (NIPT) for trisomies 21, 18, 13 and monosomy X is widely
utilized with massively parallel shotgun sequencing (MPSS), digital analysis of selected …
utilized with massively parallel shotgun sequencing (MPSS), digital analysis of selected …
Influence of fibroids on cell‐free DNA screening accuracy
F Scott, M Menezes, ME Smet, K Carey… - … in Obstetrics & …, 2022 - Wiley Online Library
ABSTRACT Objective Cell‐free DNA (cfDNA) screening assesses both maternal and
placental cfDNA. Fibroids are common and release cfDNA into maternal serum. Genetic …
placental cfDNA. Fibroids are common and release cfDNA into maternal serum. Genetic …
[HTML][HTML] The value of combined detailed first-trimester ultrasound–biochemical analysis for screening fetal aneuploidy in the era of non-invasive prenatal testing
C Ye, H Duan, M Liu, J Liu, J Xiang, Y Yin… - Archives of Gynecology …, 2023 - Springer
Purpose This study aimed to investigate the performance, cost-effectiveness and additional
findings of combined detailed ultrasound and biochemical screening for risks of major fetal …
findings of combined detailed ultrasound and biochemical screening for risks of major fetal …
[HTML][HTML] Patient attitudes and preferences about expanded noninvasive prenatal testing
ML Dubois, PD Winters, MA Rodrigue, J Gekas - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: Noninvasive prenatal testing (NIPT) using cell-free DNA (cfDNA) is typically
carried out to screen for common fetal chromosomal anomalies, with the option to screen for …
carried out to screen for common fetal chromosomal anomalies, with the option to screen for …
[HTML][HTML] Multisite assessment of the impact of cell-free DNA-based screening for rare autosomal aneuploidies on pregnancy management and outcomes
T Mossfield, E Soster, M Menezes, G Agenbag… - Frontiers in …, 2022 - frontiersin.org
Cell-free (cf) DNA screening is a noninvasive prenatal screening approach that is typically
used to screen for common fetal trisomies, with optional screening for sex chromosomal …
used to screen for common fetal trisomies, with optional screening for sex chromosomal …
Focus on the frontier issue: progress in noninvasive prenatal screening for fetal trisomy from clinical perspectives
M Tian, L Feng, J Li, R Zhang - Critical Reviews in Clinical …, 2023 - Taylor & Francis
The discovery of cell-free fetal DNA (cffDNA) in maternal blood and the rapid development of
massively parallel sequencing have revolutionized prenatal testing from invasive to …
massively parallel sequencing have revolutionized prenatal testing from invasive to …
[HTML][HTML] Noninvasive prenatal screening for trisomy 21 in patients with a vanishing twin
P Kleinfinger, A Luscan, L Descourvieres, D Buzas… - Genes, 2022 - mdpi.com
A vanishing twin (VT) occurs in up to 30% of early diagnosed twin pregnancies and is
associated with an increased risk of fetal aneuploidy. Here, we describe our experience in a …
associated with an increased risk of fetal aneuploidy. Here, we describe our experience in a …
Performance of a cell‐free DNA prenatal screening test, choice of prenatal procedure, and chromosome conditions identified during pregnancy after low‐risk cell‐free …
KL Scarff, N Flowers, CJ Love, AD Archibald… - Prenatal …, 2023 - Wiley Online Library
Objectives To evaluate the performance of cell‐free DNA (cfDNA) screening for common
fetal aneuploidies, choice of prenatal procedure, and chromosome conditions identified …
fetal aneuploidies, choice of prenatal procedure, and chromosome conditions identified …