[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Imaging the role of inflammation in mood and anxiety-related disorders

JC Felger - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Age-dependent dysregulation of innate immunity

AC Shaw, DR Goldstein, RR Montgomery - Nature Reviews …, 2013 - nature.com
As we age, the innate immune system becomes dysregulated and is characterized by
persistent inflammatory responses that involve multiple immune and non-immune cell types …

[HTML][HTML] The origins and drivers of insulin resistance

AMF Johnson, JM Olefsky - Cell, 2013 - cell.com
Obesity-induced insulin resistance is the major determinant of metabolic syndrome, which
precedes the development of type 2 diabetes mellitus and is thus the driving force behind …

Obesity and C‐reactive protein in various populations: a systematic review and meta‐analysis

J Choi, L Joseph, L Pilote - Obesity reviews, 2013 - Wiley Online Library
Obesity has been associated with elevated levels of C‐reactive protein (CRP), a marker of
inflammation and predictor of cardiovascular risk. The objective of this systematic review and …

Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases

N Sallam, I Laher - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Despite the wealth of epidemiological and experimental studies indicating the protective role
of regular physical activity/exercise training against the sequels of aging and cardiovascular …

Discrimination and systemic inflammation: a critical review and synthesis

AG Cuevas, AD Ong, K Carvalho, T Ho… - Brain, behavior, and …, 2020 - Elsevier
Exposure to discrimination or unfair treatment has emerged as an important risk factor for
illness and disease that disproportionately affects racial and ethnic minorities. Discriminatory …

Immune system to brain signaling: neuropsychopharmacological implications

L Capuron, AH Miller - Pharmacology & therapeutics, 2011 - Elsevier
There has been an explosion in our knowledge of the pathways and mechanisms by which
the immune system can influence the brain and behavior. In the context of inflammation, pro …