[HTML][HTML] Phytocannabinoids: origins and biosynthesis
T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
The promise of adolescence: Realizing opportunity for all youth
EP Backes, RJ Bonnie - 2019 - books.google.com
Adolescenceâ€" beginning with the onset of puberty and ending in the mid-20sâ€" is a
critical period of development during which key areas of the brain mature and develop …
critical period of development during which key areas of the brain mature and develop …
Cannabidiol adverse effects and toxicity
MA Huestis, R Solimini, S Pichini… - Current …, 2019 - ingentaconnect.com
Background: Currently, there is a great interest in the potential medical use of cannabidiol
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …
[HTML][HTML] Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders
MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …
Molecular targets of the phytocannabinoids: a complex picture
P Morales, DP Hurst, PH Reggio - Phytocannabinoids: Unraveling the …, 2017 - Springer
For centuries, hashish and marihuana, both derived from the Indian hemp Cannabis sativa
L., have been used for their medicinal, as well as, their psychotropic effects. These effects …
L., have been used for their medicinal, as well as, their psychotropic effects. These effects …
Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
RB Laprairie, AM Bagher, MEM Kelly… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Cannabidiol has been reported to act as an antagonist at
cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid …
cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid …
Lower-risk cannabis use guidelines: a comprehensive update of evidence and recommendations
Background. Cannabis use is common in North America, especially among young people,
and is associated with a risk of various acute and chronic adverse health outcomes …
and is associated with a risk of various acute and chronic adverse health outcomes …
[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders
EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …
drug that in recent years has drawn increasing interest as a treatment for a range of …
Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …
EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …
Allosteric and orthosteric pharmacology of cannabidiol and cannabidiol‐dimethylheptyl at the type 1 and type 2 cannabinoid receptors
M Tham, O Yilmaz, M Alaverdashvili… - British journal of …, 2019 - Wiley Online Library
Background and Purpose We sought to understand why (−)‐cannabidiol (CBD) and (−)‐
cannabidiol‐dimethylheptyl (CBD‐DMH) exhibit distinct pharmacology, despite near …
cannabidiol‐dimethylheptyl (CBD‐DMH) exhibit distinct pharmacology, despite near …