The development and application of emerging technologies of Industry 4.0 enable the
realization of digital twins (DT), which facilitates the transformation of the manufacturing …

Recently, the pharmaceutical industry has been facing several challenges associated to the
use of outdated development and manufacturing technologies. The return on investment on …

The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …

This multiauthor review article aims to bring readers up to date with some of the current
trends in the field of process analytical technology (PAT) by summarizing each aspect of the …

Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

Currently, pharmaceutical production is making the switch from batch processing towards
continuous processing. The quality of intermediate and end products produced by batch …

The implementation of process analytical technology and continuous manufacturing at an
FDA approved commercial manufacturing site is described. In this direct compaction process …

Continuous bioprocessing is significantly changing the biological drugs (or biologics)
manufacturing landscape by potentially improving product quality, process stability, and …

Continuous manufacturing has attracted increasing research attention in the pharmaceutical
industry within the last decade. Based on the extensive experimental studies, numerous …

The implementation of continuous pharmaceutical manufacturing requires advanced control
strategies rather than traditional end product testing or an operation within a small range of …