[HTML][HTML] Memory Circuits in Dementia: The Engram, Hippocampal Neurogenesis and Alzheimer's disease
O Lazarov, M Gupta, P Kumar, Z Morrissey… - Progress in …, 2024 - Elsevier
Here, we provide an in-depth consideration of our current understanding of engrams,
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …
spanning from molecular to network levels, and hippocampal neurogenesis, in health and …
Neural circuit mechanisms of acupuncture effect: where are we now?
X Wang, J Wang, R Han, C Yu, F Shen - Frontiers in Neurology, 2024 - frontiersin.org
Recently, there has been increasing attention on the impact of acupuncture on the
dysregulated neural circuits in different disease. This has led to new understandings of how …
dysregulated neural circuits in different disease. This has led to new understandings of how …
Subthalamic Nucleus Stimulation Modulates Cognitive Theory of Mind in Parkinson's Disease
H Xiao, L Lang, Z Ye, J Wu - Movement Disorders, 2024 - Wiley Online Library
Abstract Background Theory of mind (ToM), the ability to infer others' mental state, is
essential for social interaction among human beings. It has been widely reported that both …
essential for social interaction among human beings. It has been widely reported that both …
Distributed representations of innate behaviors in the hypothalamus do not predict specialized functional centers
S Stagkourakis, G Spigolon, M Marks, M Feyder, J Kim… - bioRxiv, 2023 - biorxiv.org
Survival behaviors are orchestrated by hardwired circuits located in deep subcortical brain
regions, most prominently the hypothalamus. Artificial activation of spatially localized …
regions, most prominently the hypothalamus. Artificial activation of spatially localized …
[HTML][HTML] Single cell spatial transcriptomics reveals distinct patterns of dysregulation in non-neuronal and neuronal cells induced by the Trem2R47H Alzheimer's risk …
K Johnston, BB Berackey, KM Tran, A Gelber… - Research …, 2023 - ncbi.nlm.nih.gov
METHODS We profiled 15 mouse brain sections consisting of wild-type, Trem2 R47H,
5xFAD and Trem2 R47H; 5xFAD genotypes using MERFISH spatial transcriptomics. Single …
5xFAD and Trem2 R47H; 5xFAD genotypes using MERFISH spatial transcriptomics. Single …
Mechanisms and optogenetic control of rhythm slowing associated with Alzheimer's disease: some views from dynamical modeling
Z Shen, H Zhang, L Du, Y Zhang, X Sun - Nonlinear Dynamics, 2024 - Springer
This paper aims to explain and expand the dynamic mechanisms underlying the interesting
but controversial experimental phenomena in the optogenetic regulation of Alzheimer's …
but controversial experimental phenomena in the optogenetic regulation of Alzheimer's …
Bayesian inference and role of astrocytes in amyloid-beta dynamics with modelling of Alzheimer's disease using clinical data
H Shaheen, R Melnik, TADN Initiative - arXiv preprint arXiv:2306.12520, 2023 - arxiv.org
Alzheimer's disease (AD) is a prominent, worldwide, age-related neurodegenerative
disease that currently has no systemic treatment. Strong evidence suggests that permeable …
disease that currently has no systemic treatment. Strong evidence suggests that permeable …
[HTML][HTML] Anatomically distributed neural representations of instincts in the hypothalamus
S Stagkourakis, G Spigolon, M Marks, M Feyder, J Kim… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Artificial activation of anatomically localized, genetically defined hypothalamic neuron
populations is known to trigger distinct innate behaviors, suggesting a hypothalamic nucleus …
populations is known to trigger distinct innate behaviors, suggesting a hypothalamic nucleus …
[HTML][HTML] Advancing Alzheimer's care: a novel therapy with lecanemab
A Teli, P Dhande - The Egyptian Journal of Neurology, Psychiatry and …, 2023 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects the
patient's quality of life. The current regime of drugs only halts the symptoms of the disease …
patient's quality of life. The current regime of drugs only halts the symptoms of the disease …
[HTML][HTML] Elevated plasma neurofilament light was associated with multi-modal neuroimaging features in Alzheimer's Disease signature regions and predicted future …
Q Hu, M Shi, Y Li, X Zhao - Research Square, 2024 - ncbi.nlm.nih.gov
Background: Neurofilament Light (NfL) is a biomarker for early neurodegeneration in
Alzheimer's disease (AD). This study aims to examine the association between plasma NfL …
Alzheimer's disease (AD). This study aims to examine the association between plasma NfL …