Phosphorus, present as phosphate in biological systems, is an essential mineral for various
biological activities and biochemical processes. Numerous studies have indicated that …

Na+-glucose cotransporter-2 (SGLT2) inhibitors are the new mainstay of treatment for
diabetes mellitus and cardiovascular diseases. Despite the remarkable benefits, the …

Cardiovascular (CV) disease is highly prevalent in the population with chronic kidney
disease (CKD), where the risk of CV death in early stages far exceeds the risk of progression …

Phosphorus is one of the most abundant minerals in the human body. It is essential for
almost all biochemical activities through ATP formation, intracellular signal transduction, cell …

Cellular senescence is one type of permeant arrest of cell growth and one of increasingly
recognized contributor to aging and age-associated disease. High phosphate and low …

Activin A is a new fascinating player in chronic kidney disease-mineral and bone disorder
(CKD-MBD), which is implicated in progressive renal disease, vascular calcification, and …

Hypertension (HPT) is the leading modifiable risk factor for cardiovascular diseases and
premature death worldwide. Currently, attention is given to various dietary approaches with …

Pharmacologic intervention is one of the cornerstones of management for hypertension.
However, potential adverse drug reactions, drug-drug interaction, as well as safety and …

Background Hyperphosphatemia occurs frequently in end-stage renal disease patients on
hemodialysis and is associated with increased mortality. Hyperphosphatemia contributes to …

Phosphate is essential for proper cell function by providing the fundamentals for DNA,
cellular structure, signaling and energy production. The homeostasis of phosphate is …