Assembly‐driven protection from hydrolysis as key selective force during chemical evolution
R Edri, S Fisher, C Menor‐Salvan, LD Williams… - FEBS …, 2023 - Wiley Online Library
The origins of biopolymers pose fascinating questions in prebiotic chemistry. The marvelous
assembly proficiencies of biopolymers suggest they are winners of a competitive …
assembly proficiencies of biopolymers suggest they are winners of a competitive …
The Role of Hydrogen Bonds in Thermally Responsive Crystallization‐Driven Template Autocatalysis
Autocatalysis has been recognized to be involved in the emergence of life and intrinsic to
biomolecular replication. Recently, an efficient template autocatalysis driven by solvent‐free …
biomolecular replication. Recently, an efficient template autocatalysis driven by solvent‐free …
Cysteine‐Based Dynamic Self‐Assembly and Their Importance in the Origins of Life
The knowledge regarding the origins of life from inanimate materials is still elusive. It was
proposed that biological building blocks evolved from the inorganic substances present in …
proposed that biological building blocks evolved from the inorganic substances present in …
Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity
D Komáromy, T Tiemersma-Wegman, J Kemmink… - Chem, 2021 - cell.com
Self-assembly enables access to complex molecular architectures but is traditionally
confined to structures that represent global minima on the Gibbs energy landscape. We now …
confined to structures that represent global minima on the Gibbs energy landscape. We now …
Introducing charge transfer functionality into prebiotically relevant β-sheet peptide fibrils
D Ivnitski, M Amit, B Rubinov, R Cohen-Luria… - Chemical …, 2014 - pubs.rsc.org
Incorporation of naphthalene diimide moieties as side chains of short amphiphilic peptide
results in the formation of fibrils that exhibit substantial intermolecular π-stacking …
results in the formation of fibrils that exhibit substantial intermolecular π-stacking …
De Novo Designed α‐Helical Coiled‐Coil Peptides as Scaffolds for Chemical Reactions
WM Rink, F Thomas - Chemistry–A European Journal, 2019 - Wiley Online Library
Coiled coils (CCs) are well‐understood protein‐folding motifs. They appear in a variety of
oligomer states and as homo‐and heteromeric assemblies. This versatility and the general …
oligomer states and as homo‐and heteromeric assemblies. This versatility and the general …
Sequence decoding of 1D to 2D self‐assembling cyclic peptides
The inherent ability of peptides to self‐assemble with directional and rationally predictable
interactions has fostered a plethora of synthetic two‐dimensional (2D) supramolecular …
interactions has fostered a plethora of synthetic two‐dimensional (2D) supramolecular …
The Systems Chemistry of Nucleic‐acid‐Peptide Networks
A Kumar Bandela, H Sadihov‐Hanoch… - Israel Journal of …, 2022 - Wiley Online Library
Living cells use chemical building blocks (biopolymers) to form fascinatingly complex
architectures, which in turn display multiple functions necessary for the cell life cycle. The …
architectures, which in turn display multiple functions necessary for the cell life cycle. The …
Polymorphism in peptide self-assembly visualized
M Tirrell - Proceedings of the National Academy of …, 2022 - National Acad Sciences
The spontaneous formation of well-defined supramolecular structures, based on precisely
located, finely balanced, and weak, relative to kT, interactions among the assembling …
located, finely balanced, and weak, relative to kT, interactions among the assembling …