Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label …

L Xuan, Y Wang, F Huang, Z Fan, Y Xu, J Sun… - The Lancet …, 2020 - thelancet.com
Background Findings of retrospective studies suggest that sorafenib maintenance post-
transplantation might reduce relapse in patients with FLT3 internal tandem duplication (FLT3 …

Venetoclax plus 3+ 7 daunorubicin and cytarabine chemotherapy as first-line treatment for adults with acute myeloid leukaemia: a multicentre, single-arm, phase 2 trial

H Wang, L Mao, M Yang, P Qian, H Lu… - The Lancet …, 2022 - thelancet.com
Background Adults with acute myeloid leukaemia have unsatisfactory clinical outcomes and
rates of complete remission. Venetoclax combined with azacytidine or low-dose cytarabine …

Clinical characteristics, drug resistance and death risk factors of Burkholderia cepacia infection in hematopoietic stem cell transplant patients

Y Jia, Y Liu, Y Liu, K Yang, Y Liu - BMC Infectious Diseases, 2022 - Springer
Background Burkholderia cepacia (BC) has been detected more and more in infected
patients in recent years. However, as a high-risk population, the clinical characteristics and …

Interferon-α as maintenance therapy can significantly reduce relapse in patients with favorable-risk acute myeloid leukemia

H Jiang, XH Liu, J Kong, J Wang, JS Jia… - Leukemia & …, 2021 - Taylor & Francis
To evaluate the efficacy of interferon-α (IFN-α) as maintenance therapy in patients with
favorable-risk acute myeloid leukemia (AML), this retrospective study enrolled 84 patients …

Venetoclax combined with daunorubicin and cytarabine (2+ 6) as induction treatment in adults with newly diagnosed acute myeloid leukemia: a phase 2, multicenter …

X Suo, F Zheng, D Wang, L Zhao, J Liu, L Li… - … Hematology & Oncology, 2023 - Springer
Abstract Background Venetoclax (Ven) combined with intensive chemotherapy was proven
effective in the management of acute myeloid leukemia (AML). However, the severe and …

Landscape of T cells in NK-AML (M4/M5) revealed by single-cell sequencing

W Wu, X Liang, H Li, X Huang, C Wan… - Journal of Leukocyte …, 2022 - academic.oup.com
Normal karyotype acute myeloid leukemia (NK-AML) is a highly heterogeneous malignancy
that resides within a complex immune microenvironment, complicating efforts to reveal the …

Comparison of haploidentical hematopoietic stem cell transplantation with chemotherapy in older adults with acute myeloid leukemia

YQ Sun, XH Zhang, Q Jiang, H Jiang… - Bone Marrow …, 2023 - nature.com
Acute myeloid leukemia (AML) outcomes are very poor in older patients. Haploidentical
stem cell transplantation (haplo-SCT) helps to achieve long-term survival. However, the …

Establishment and validation of a carbohydrate metabolism-related gene signature for prognostic model and immune response in acute myeloid leukemia

Y Yang, Y Yang, J Liu, Y Zeng, Q Guo, J Guo… - Frontiers in …, 2022 - frontiersin.org
Introduction The heterogeneity of treatment response in acute myeloid leukemia (AML)
patients poses great challenges for risk scoring and treatment stratification. Carbohydrate …

Dihydropyrimidinase‐like 2 can serve as a novel therapeutic target and prognostic biomarker in acute myeloid leukemia

F Li, Q Ling, J Lian, Y Chen, C Hu, M Yang… - Cancer …, 2023 - Wiley Online Library
Background Identifying therapeutic targets and prognostic biomarkers significantly
contributes to individualized treatment of acute myeloid leukemia (AML) …

Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis

F Li, W Ye, Y Yao, W Wei, X Lin, H Zhuang, C Li… - Journal of Translational …, 2023 - Springer
Background Spermatogenesis associated serine rich 2 like (SPATS2L) was highly
expressed in homoharringtonine (HHT) resistant acute myeloid leukemia (AML) cell lines …