Molecular Footprints on Osmoregulation-Related Genes Associated with Freshwater Colonization by Cetaceans and Sirenians

E Ramos, G Selleghin-Veiga, L Magpali… - Journal of molecular …, 2023 - Springer
The genetic basis underlying adaptive physiological mechanisms has been extensively
explored in mammals after colonizing the seas. However, independent lineages of aquatic …

Evolink: a phylogenetic approach for rapid identification of genotype–phenotype associations in large-scale microbial multispecies data

Y Yang, X Jiang - Bioinformatics, 2023 - academic.oup.com
Motivation The discovery of the genetic features that underly a phenotype is a fundamental
task in microbial genomics. With the growing number of microbial genomes that are paired …

[HTML][HTML] Repeated evolution of similar phenotypes: Integrating comparative methods with developmental pathways

AG Pereira, T Kohlsdorf - Genetics and molecular biology, 2023 - SciELO Brasil
Repeated phenotypes, often referred to as 'homoplasies' in cladistic analyses, may evolve
through changes in developmental processes. Genetic bases of recurrent evolution gained …

Unraveling the Environment-Phenotype-Genotype Nexus: Successful Approaches from Bird Colors and How to Apply Them to Other Traits and Taxa

RS Marcondes - The Quarterly Review of Biology, 2024 - journals.uchicago.edu
Demonstrating the genetic and environmental bases of adaptive phenotypes is a central
goal of biology. Bird colors have a storied tradition at the forefront of conceptual advances in …

WGCCRR: a web-based tool for genome-wide screening of convergent indels and substitutions of amino-acids

Z Dong, C Wang, Q Qu - Bioinformatics Advances, 2024 - academic.oup.com
Genome-wide analyses of protein-coding gene sequences are being employed to examine
the genetic basis of adaptive evolution in many organismal groups. Previous studies have …

[HTML][HTML] Genes underlying the evolution of tetrapod testes size

J Baker, A Meade, C Venditti - BMC biology, 2021 - Springer
Background Testes vary widely in mass relative to body mass across species, but we know
very little about which genes underlie and contribute to such variation. This is partly because …

[HTML][HTML] Roles of the crucial mitochondrial DNA in hypertrophic cardiomyopathy prognosis and diagnosis: A review

X Liao, S Zhou, D Zeng, W Ying, D Lian, M Zhang… - Medicine, 2023 - journals.lww.com
Mitochondrial DNA is implicated in hypertrophic cardiomyopathy (HCM) development. We
aimed to identify valuable mtDNAs that contribute to the development of HCM. Differentially …

[HTML][HTML] Comparative transcriptomics highlights convergent evolution of energy metabolic pathways in group-living spiders

H Yang, B Lyu, HQ Yin, SQ Li - Zoological research, 2021 - ncbi.nlm.nih.gov
Although widely thought to be aggressive, solitary, and potentially cannibalistic, some spider
species have evolved group-living behaviors. The distinct transition provides the framework …

[HTML][HTML] RERconverge Expansion: Using Relative Evolutionary Rates to Study Complex Categorical Trait Evolution

R Redlich, A Kowalczyk, M Tene, HH Sestili, K Foley… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Comparative genomics approaches seek to associate evolutionary genetic changes with the
evolution of phenotypes across a phylogeny. Many of these methods, including our …

A cautionary tale on proper use of branch-site models to detect convergent positive selection

A Kowalczyk, M Chikina, NL Clark - bioRxiv, 2021 - biorxiv.org
Comparative genomics has become a powerful tool to elucidate genotype-phenotype
relationships, particularly through the study of convergently acquired phenotypes. By …