Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …

Acetylcholine (AC h) plays an important role in memory function and has been implicated in
aging‐related dementia, in which the impairment of hippocampus‐dependent learning …

Attention is critical to high-level cognition and attention deficits are a hallmark of neurologic
and neuropsychiatric disorders. Although years of research indicates that distinct …

Classical Hebbian learning puts the emphasis on joint pre-and postsynaptic activity, but
neglects the potential role of neuromodulators. Since neuromodulators convey information …

Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

Attention exerts a strong influence over neuronal processing in cortical areas,. It selectively
increases firing rates,, and affects tuning properties,, including changing receptive field …

Recent theoretical work has provided a basic understanding of signal propagation in
networks of spiking neurons, but mechanisms for gating and controlling these signals have …

Rhythmic activity of neuronal ensembles has been proposed to play an important role in
cognitive functions such as attention, perception, and memory. Here we investigate whether …

Acetylcholine plays an important role in cognitive function, as shown by pharmacological
manipulations that impact working memory, attention, episodic memory and spatial memory …

The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-
range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction …