Long non-coding RNAs and rheumatoid arthritis: pathogenesis and clinical implications

O Elazazy, HM Midan, RK Shahin, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) are a class of noncoding RNAs with a length larger than
200 nucleotides that participate in various diseases and biological processes as they can …

[HTML][HTML] Circular RNA vaccine in disease prevention and treatment

D Niu, Y Wu, J Lian - Signal transduction and targeted therapy, 2023 - nature.com
CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology.
In the decades since its initial discovery, their biogenesis, regulation, and function have …

Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19

M Aznaourova, N Schmerer, H Janga… - Proceedings of the …, 2022 - National Acad Sciences
The systemic immune response to viral infection is shaped by master transcription factors,
such as NF-κB, STAT1, or PU. 1. Although long noncoding RNAs (lncRNAs) have been …

The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2

T Vierbuchen, S Agarwal, JL Johnson… - Proceedings of the …, 2023 - National Acad Sciences
The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative
feedback regulator of type I interferon and inflammatory cytokine expression in human …

Translation and emerging functions of non‐coding RNAs in inflammation and immunity

E Della Bella, J Koch, K Baerenfaller - Allergy, 2022 - Wiley Online Library
Regulatory non‐coding RNAs (ncRNAs) including small non‐coding RNAs (sRNAs), long
non‐coding RNAs (lncRNAs), and circular RNAs (circRNAs) have gained considerable …

[HTML][HTML] The emerging roles of long non-coding RNA in host immune response and intracellular bacterial infections

A Arunima, EJ van Schaik, JE Samuel - Frontiers in cellular and …, 2023 - frontiersin.org
The long non-coding RNAs (lncRNAs) are evolutionarily conserved classes of non-coding
regulatory transcripts of> 200 nucleotides in length. They modulate several transcriptional …

[HTML][HTML] An Overview of the Immune Modulatory Properties of Long Non-Coding RNAs and Their Potential Use as Therapeutic Targets in Cancer

M Martinez-Castillo, A M. Elsayed, G López-Berestein… - Non-coding RNA, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) play pivotal roles in regulating immune responses,
immune cell differentiation, activation, and inflammatory processes. In cancer, they are …

LncRNA MIAT regulates autophagy and apoptosis of macrophage infected by mycobacterium tuberculosis through the miR-665/ULK1 signaling axis

F Jiang, J Lou, X Zheng, X Yang - Molecular Immunology, 2021 - Elsevier
Accumulating lines of evidence have revealed the involvement of long non-coding RNAs
(lncRNAs) in the control and elimination of invading Mycobacterium tuberculosis (Mtb) by …

[HTML][HTML] Expression of steroid receptor RNA activator 1 (SRA1) in the adipose tissue is associated with TLRs and IRFs in diabesity

S Kochumon, H Arefanian, S Sindhu, R Thomas… - Cells, 2022 - mdpi.com
Steroid receptor RNA activator gene (SRA1) emerges as a player in pathophysiological
responses of adipose tissue (AT) in metabolic disorders such as obesity and type 2 diabetes …

[HTML][HTML] An integrated analysis of mRNAs, lncRNAs, and miRNAs based on weighted gene co-expression network analysis involved in bovine endometritis

N Sheybani, MR Bakhtiarizadeh, A Salehi - Scientific reports, 2021 - nature.com
In dairy cattle, endometritis is a severe infectious disease that occurs following parturition. It
is clear that genetic factors are involved in the etiology of endometritis, however, the …