Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …
The genetics of polycystic ovary syndrome: an overview of candidate gene systematic reviews and genome-wide association studies
Polycystic Ovary Syndrome (PCOS) is a complex condition with mechanisms likely to involve
the interaction between genetics and lifestyle. Familial clustering of PCOS symptoms is well …
the interaction between genetics and lifestyle. Familial clustering of PCOS symptoms is well …
[HTML][HTML] Physiology, ovulation
JE Holesh, AN Bass, M Lord - 2017 - europepmc.org
Ovulation is a physiologic process defined by the rupture and release of the dominant follicle
from the ovary into the fallopian tube where it has the potential to become fertilized. The …
from the ovary into the fallopian tube where it has the potential to become fertilized. The …
Improvement effect of metformin on female and male reproduction in endocrine pathologies and its mechanisms
AO Shpakov - Pharmaceuticals, 2021 - mdpi.com
Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …
combination with other drugs, restores the ovarian function in women with polycystic ovary …
An overview of FSH-FSHR biology and explaining the existing conundrums
D Bhartiya, H Patel - Journal of Ovarian Research, 2021 - Springer
FSH was first identified in 1930 and is central to mammalian reproduction. It is indeed
intriguing that despite being researched upon for about 90 years, there is still so much more …
intriguing that despite being researched upon for about 90 years, there is still so much more …
The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development: the state of the art
V Bruni, A Capozzi, S Lello - Reproductive Sciences, 2022 - Springer
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disease affecting about 20–
25% of women in reproductive age. Different mechanisms could contribute to the …
25% of women in reproductive age. Different mechanisms could contribute to the …
In search of new therapeutics—molecular aspects of the PCOS pathophysiology: genetics, hormones, metabolism and beyond
A Wawrzkiewicz-Jałowiecka, K Kowalczyk… - International Journal of …, 2020 - mdpi.com
In a healthy female reproductive system, a subtle hormonal and metabolic dance leads to
repetitive cyclic changes in the ovaries and uterus, which make an effective ovulation and …
repetitive cyclic changes in the ovaries and uterus, which make an effective ovulation and …
ERβ regulation of gonadotropin responses during folliculogenesis
EB Lee, VP Chakravarthi, MW Wolfe… - International journal of …, 2021 - mdpi.com
Gonadotropins are essential for regulating ovarian development, steroidogenesis, and
gametogenesis. While follicle stimulating hormone (FSH) promotes the development of …
gametogenesis. While follicle stimulating hormone (FSH) promotes the development of …
Actions and roles of FSH in germinative cells
Follicle stimulating hormone (FSH) is produced by the pituitary gland in a coordinated
hypothalamic–pituitary–gonadal (HPG) axis event, plays important roles in reproduction and …
hypothalamic–pituitary–gonadal (HPG) axis event, plays important roles in reproduction and …
Gonadotropins as pharmacological agents in assisted reproductive technology and polycystic ovary syndrome
R Singh, S Kaur, S Yadav, S Bhatia - Trends in Endocrinology & Metabolism, 2023 - cell.com
Polycystic ovary syndrome (PCOS) is a complex endocrinopathy associated with
subfertility/infertility and pregnancy complications. Most PCOS women opt for assisted …
subfertility/infertility and pregnancy complications. Most PCOS women opt for assisted …