Systems biology of malaria explored with nonhuman primates
MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
generations of scientists, since its debut in 1971, and remains pertinent to the present day …
Molecular markers for malaria genetic epidemiology: progress and pitfalls
Over recent years, progress in molecular markers for genotyping malaria parasites has
enabled informative studies of epidemiology and transmission dynamics. Results have …
enabled informative studies of epidemiology and transmission dynamics. Results have …
Drug resistance and vaccine target surveillance of Plasmodium falciparum using nanopore sequencing in Ghana
ST Girgis, E Adika, FE Nenyewodey… - Nature …, 2023 - nature.com
Malaria results in over 600,000 deaths annually, with the highest burden of deaths in young
children living in sub-Saharan Africa. Molecular surveillance can provide important …
children living in sub-Saharan Africa. Molecular surveillance can provide important …
Ancient diversity in host-parasite interaction genes in a model parasitic nematode
L Stevens, I Martínez-Ugalde, E King, M Wagah… - Nature …, 2023 - nature.com
Host-parasite interactions exert strong selection pressures on the genomes of both host and
parasite. These interactions can lead to negative frequency-dependent selection, a form of …
parasite. These interactions can lead to negative frequency-dependent selection, a form of …
Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia
Background Genomic surveillance is crucial for monitoring malaria transmission and
understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in …
understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in …
Population Genomic Evidence of Adaptive Response during the Invasion History of Plasmodium falciparum in the Americas
MJM Lefebvre, J Daron, E Legrand… - Molecular Biology …, 2023 - academic.oup.com
Plasmodium falciparum, the most virulent agent of human malaria, spread from Africa to all
continents following the out-of-Africa human migrations. During the transatlantic slave trade …
continents following the out-of-Africa human migrations. During the transatlantic slave trade …
A Molecular Analysis of Memory B Cell and Antibody Responses Against Plasmodium falciparum Merozoite Surface Protein 1 in Children and Adults From Uganda
SJ Gonzales, KN Clarke, G Batugedara… - Frontiers in …, 2022 - frontiersin.org
Memory B cells (MBCs) and plasma antibodies against Plasmodium falciparum (Pf)
merozoite antigens are important components of the protective immune response against …
merozoite antigens are important components of the protective immune response against …
Measuring changes in Plasmodium falciparum var census population size and structure in response to sequential malaria control interventions
The diversity of Plasmodium falciparum within human hosts requires parasite population
size be defined in terms of parasite variation rather than the number of infected hosts. To …
size be defined in terms of parasite variation rather than the number of infected hosts. To …
Transcriptomic analyses of differentially expressed human genes, micro RNAs and long-non-coding RNAs in severe, symptomatic and asymptomatic malaria infection
Malaria transmission and endemicity in Africa remains hugely disproportionate compared to
the rest of the world. The complex life cycle of P. falciparum (Pf) between the vertebrate …
the rest of the world. The complex life cycle of P. falciparum (Pf) between the vertebrate …
Nanopore sequencing for real-time genomic surveillance of Plasmodium falciparum
ST Girgis, E Adika, FE Nenyewodey, DK Senoo Jnr… - bioRxiv, 2022 - biorxiv.org
Malaria is a global public health priority causing over 600,000 deaths annually, mostly
young children living in Sub-Saharan Africa. Molecular surveillance can provide key …
young children living in Sub-Saharan Africa. Molecular surveillance can provide key …